Literature DB >> 21305314

Choroidal metastasis from hepatocellular carcinoma, diagnosed by fine needle aspiration biopsy and treated by iodine-125 brachytherapy.

Lalkrushna Malaviya1, Carol L Shields, Kiran Turaka, Hormoz Ehya, Jerry A Shields.   

Abstract

PURPOSE: To report a rare case of choroidal metastasis from hepatocellular carcinoma.
METHODS: A 63-year-old man with known hepatocellular carcinoma (HCC) and treated clavicular metastasis noted reduced visual acuity in the right eye. He was found to have an amelanotic choroidal tumor measuring 18 × 14 × 9.3 mm and with retinal detachment. Fine needle aspiration biopsy confirmed metastatic HCC.
RESULTS: The choroidal metastasis was treated with 5 days of iodine-125 plaque brachytherapy (3500 cGy to apex). Tumor regression to 2.6 mm thickness with resolution of retinal detachment and preservation of visual acuity at 20/40 at the 4-month follow-up was documented.
CONCLUSIONS: HCC metastasis to the choroid can be treated with focal plaque brachytherapy, with preservation of vision and quality of life.

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Year:  2011        PMID: 21305314     DOI: 10.1007/s00417-011-1626-8

Source DB:  PubMed          Journal:  Graefes Arch Clin Exp Ophthalmol        ISSN: 0721-832X            Impact factor:   3.117


  10 in total

1.  Hepatocellular carcinoma metastatic to uvea.

Authors:  Robert Wesolowski; Jeffrey Yau-Huei Chung; Arun Singh; Richard Kim
Journal:  Retin Cases Brief Rep       Date:  2010

2.  METASTASIS OF A HEPATOMA TO THE CHOROID.

Authors:  W H TAAKE; R A ALLEN; B R STRAATSMA
Journal:  Am J Ophthalmol       Date:  1963-08       Impact factor: 5.258

3.  Plaque radiotherapy for the management of uveal metastasis.

Authors:  C L Shields; J A Shields; P De Potter; M Quaranta; J Freire; L W Brady; J Barrett
Journal:  Arch Ophthalmol       Date:  1997-02

4.  Clinical features of hepatocellular carcinoma with extrahepatic metastases.

Authors:  Mitsuteru Natsuizaka; Takumi Omura; Toru Akaike; Yasuaki Kuwata; Katsu Yamazaki; Takahiro Sato; Yoshiyasu Karino; Jouji Toyota; Toshihiro Suga; Masahiro Asaka
Journal:  J Gastroenterol Hepatol       Date:  2005-11       Impact factor: 4.029

5.  Functional vision is improved in the majority of patients treated with external-beam radiotherapy for choroid metastases: a multivariate analysis of 188 patients.

Authors:  S B Rudoler; C L Shields; B W Corn; P De Potter; T Hyslop; W J Curran; J A Shields
Journal:  J Clin Oncol       Date:  1997-03       Impact factor: 44.544

6.  Survey of 520 eyes with uveal metastases.

Authors:  C L Shields; J A Shields; N E Gross; G P Schwartz; S E Lally
Journal:  Ophthalmology       Date:  1997-08       Impact factor: 12.079

7.  Treatment of metastatic tumors of the choroid with proton beam irradiation.

Authors:  Efthymia K Tsina; Anne Marie Lane; David N Zacks; John E Munzenrider; J Michael Collier; Evangelos S Gragoudas
Journal:  Ophthalmology       Date:  2005-02       Impact factor: 12.079

8.  Fine-needle aspiration biopsy of iris tumors in 100 consecutive cases: technique and complications.

Authors:  Carol L Shields; Maria E Manquez; Hormoz Ehya; Arman Mashayekhi; Carl J Danzig; Jerry A Shields
Journal:  Ophthalmology       Date:  2006-11       Impact factor: 12.079

9.  Hepatocellular carcinoma metastatic to the orbit in an African patient.

Authors:  L Schwab; H Doshi; J A Shields; K Kagame; H Chana
Journal:  Ophthalmic Surg       Date:  1994-02

10.  [A rapidly progressed metastatic choroidal tumor from a hepatocellular carcinoma].

Authors:  Hiroko Tateno; Takeshi Hoshino; Kanji Takahashi; Miyo Matsumura; Noriko Sakaida; Chisato Ohe
Journal:  Nippon Ganka Gakkai Zasshi       Date:  2009-02
  10 in total
  1 in total

1.  Unilateral temporal haemianopia in a patient with non-small cell lung cancer: intraocular metastasis despite chemotherapy.

Authors:  Alexander Liu; Harman Saman; Pawan Pusalkar
Journal:  BMJ Case Rep       Date:  2011-07-28
  1 in total

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