Literature DB >> 21302974

Nickel-catalyzed cycloaddition of anthranilic acid derivatives to alkynes.

Nobuyoshi Maizuru1, Tasuku Inami, Takuya Kurahashi, Seijiro Matsubara.   

Abstract

A nickel-catalyzed cycloaddition has been developed where readily available anthranilic acid derivatives react with alkynes to afford substituted indoles. The reaction involves oxidative addition of Ni(0) to an ester moiety, which allows intermolecular addition to alkynes via decarbonylation and 1,3-acyl migration.

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Year:  2011        PMID： 21302974     DOI： 10.1021/ol200090g

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  4 in total

1.  Ti-Catalyzed Multicomponent Oxidative Carboamination of Alkynes with Alkenes and Diazenes.

Authors:  Zachary W Davis-Gilbert; Letitia J Yao; Ian A Tonks
Journal:  J Am Chem Soc       Date:  2016-10-28       Impact factor: 15.419

2.  New Indole Tubulin Assembly Inhibitors Cause Stable Arrest of Mitotic Progression, Enhanced Stimulation of Natural Killer Cell Cytotoxic Activity, and Repression of Hedgehog-Dependent Cancer.

Authors:  Giuseppe La Regina; Ruoli Bai; Antonio Coluccia; Valeria Famiglini; Sveva Pelliccia; Sara Passacantilli; Carmela Mazzoccoli; Vitalba Ruggieri; Annalisa Verrico; Andrea Miele; Ludovica Monti; Marianna Nalli; Romina Alfonsi; Lucia Di Marcotullio; Alberto Gulino; Biancamaria Ricci; Alessandra Soriani; Angela Santoni; Michele Caraglia; Stefania Porto; Eleonora Da Pozzo; Claudia Martini; Andrea Brancale; Luciana Marinelli; Ettore Novellino; Stefania Vultaggio; Mario Varasi; Ciro Mercurio; Chiara Bigogno; Giulio Dondio; Ernest Hamel; Patrizia Lavia; Romano Silvestri
Journal:  J Med Chem       Date:  2015-07-20       Impact factor: 7.446

Review 3.  1,2-Difunctionalizations of alkynes entailing concomitant C-C and C-N bond-forming carboamination reactions.

Authors:  Santosh Kumar Nanda; Rosy Mallik
Journal:  RSC Adv       Date:  2022-03-04       Impact factor: 3.361

4.  Synthesis of 2-Substitued Indoles via Pd-Catalysed Cyclization in an Aqueous Micellar Medium.

Authors:  Sofia Siciliano; Elena Cini; Maurizio Taddei; Giorgia Vinciarelli
Journal:  Molecules       Date:  2021-06-26       Impact factor: 4.411
  4 in total

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