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Literature DB >> 21302069

Multi-Locus control of MLC reactions in rhesus monkeys.

Abstract

The genetic basis for MLC reactivity in rhesus monkeys was further investigated. Cells from anintra-RhLA recombinant monkey were MLC reactive with those of an SD-identical sib and with each of two sets of homozygous typing cells carrying either paternal haplotype. Also, cells from a pair ofRhLA- identical sibs reacted in MLC with each other, as well as with three genotypically different siblings. This excludes control of MLC reactivity by the conventionalD locus only. Thus the results selected for presentation provide formal evidence for the existence of at least one additional MLC locus, namedD'. The possibility thatD' exerts its influence on MLC reactivity only after alloimmunization is discussed.

Entities: Species

Year: 1978 PMID： 21302069 DOI： 10.1007/BF01844001

Source DB: PubMed Journal: Immunogenetics ISSN： 0093-7711 Impact factor: 2.846

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References

26 in total

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Authors: A A van Es; R L Marquet; W van Vreeswijk; B Tank; H Balner
Journal: Transplant Proc Date: 1977-03 Impact factor: 1.066

2. Three closely linked genetic systems relevant to transplantation.

Authors: E J Yunis; D B Amos
Journal: Proc Natl Acad Sci U S A Date: 1971-12 Impact factor: 11.205

3. Multiple MLC (LD) determinants on the same HL-A haplotype.

Authors: B Dupont; C Jersild; G S Hansen; L S Nielsen; M Thomsen; A Svejgaard
Journal: Transplant Proc Date: 1973-12 Impact factor: 1.066

Review 4. Current knowledge of the histocompatibility complex of rhesus monkeys.

Authors: H Balner
Journal: Transplant Rev Date: 1973

5. MLR in families with an HL-A haplotype shared by parents: recombination between SD2 and LD2 and possible evidence for an LD3 locus.

Authors: M Sasportes; C Mawas; A Bernard; Y Christen; J Dausset
Journal: Transplant Proc Date: 1973-12 Impact factor: 1.066

Multi-Locus control of MLC reactions in rhesus monkeys.

1. Influence of matching for RhLA (SD) antigens and of mixed lymphocyte reactivity on allograft survival in unrelated rhesus monkeys.

2. Three closely linked genetic systems relevant to transplantation.

3. Multiple MLC (LD) determinants on the same HL-A haplotype.

Review 4. Current knowledge of the histocompatibility complex of rhesus monkeys.

5. MLR in families with an HL-A haplotype shared by parents: recombination between SD2 and LD2 and possible evidence for an LD3 locus.

6. [Position of a locus determining mixed lymphocyte reaction distinct from the known HL-A loci].

7. A major role for the Ir-1 region of the mouse H-2 complex in the mixed leukocyte reaction.

8. Mixed lymphocyte reactivity in rhesus sibships.

9. The major histocompatibility complex of rhesus monkeys. VI. Serology and genetics of Ia-like antigens.

10. Serologically defined and lymphocyte-defined components of the major histocompatibility complex in the mouse.