Literature DB >> 21301752

The first chemical synthesis of boronic acid-modified DNA through a copper-free click reaction.

Chaofeng Dai1, Lifang Wang, Jia Sheng, Hanjing Peng, Alexander Boryanov Draganov, Zhen Huang, Binghe Wang.   

Abstract

The first chemical incorporation of the boronic acid group into DNA using a copper-free click reagent was reported. Compared with the PCR-based method, this approach allows for site-specific incorporation and synthesis on a larger scale.

Entities:  

Mesh：

Substances：

Year:  2011        PMID： 21301752     DOI： 10.1039/c0cc04546b

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  4 in total

1.  Post-synthesis DNA modifications using a trans-cyclooctene click handle.

Authors:  Ke Wang; Danzhu Wang; Kaili Ji; Weixuan Chen; Yueqin Zheng; Chaofeng Dai; Binghe Wang
Journal:  Org Biomol Chem       Date:  2015-01-21       Impact factor: 3.876

2.  Rapid and specific post-synthesis modification of DNA through a biocompatible condensation of 1,2-aminothiols with 2-cyanobenzothiazole.

Authors:  Yunfeng Cheng; Hanjing Peng; Weixuan Chen; Nanting Ni; Bowen Ke; Chaofeng Dai; Binghe Wang
Journal:  Chemistry       Date:  2013-02-28       Impact factor: 5.236

3.  Hydrogen peroxide-triggered gene silencing in mammalian cells through boronated antisense oligonucleotides.

Authors:  Shohei Mori; Kunihiko Morihiro; Takumi Okuda; Yuuya Kasahara; Satoshi Obika
Journal:  Chem Sci       Date:  2017-12-06       Impact factor: 9.825

4.  Click-Particle Display for Base-Modified Aptamer Discovery.

Authors:  Chelsea K L Gordon; Diana Wu; Anusha Pusuluri; Trevor A Feagin; Andrew T Csordas; Michael S Eisenstein; Craig J Hawker; Jia Niu; Hyongsok Tom Soh
Journal:  ACS Chem Biol       Date:  2019-10-12       Impact factor: 5.100
  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.