Literature DB >> 21297757

The role of alcohol as a co-carcinogen.

S Cohen.   

Abstract

If cancer occurs because of what we eat, what we drink, what we smoke, and to some extent where we live and work, it follows that over 80% of cancers in human beings are related to environmental causes and therefore preventable.Since virtually every major chemical is under investigation for its carcinogenic effect, it is high time that the biological impact of alcohol received more than scant attention from the health professions as a lifestyle chemical which may be a factor in the commencement or promotion of modern man's most deadly disease.Clinical and epidemiological studies have implicated the excessive use of alcohol with the risk of developing certain cancers, especially when combined with heavy smoking. Other factors associated with drinking and increased risk of cancer consist of geographic, racial, sex and organ specificity, variations of which must be borne in mind in any study of potential environmental hazards.Research is currently under way to determine whether certain alcohol beverages may contain carcinogens, which may focus attention on the role of heavy drinking as one additional environmental factor in the spectrum of exogenous agents related to cancer production.

Entities:  

Year:  1979        PMID: 21297757      PMCID: PMC2383124     

Source DB:  PubMed          Journal:  Can Fam Physician        ISSN: 0008-350X            Impact factor:   3.275


  42 in total

1.  THE RELATIONSHIP OF THE USE OF TOBACCO AND ALCOHOL TO CANCER OF THE ORAL CAVITY, PHARYNX OR LARYNX.

Authors:  R G VINCENT; F MARCHETTA
Journal:  Am J Surg       Date:  1963-09       Impact factor: 2.565

2.  [Alcohol and cancer. Results of a retrospective investigation].

Authors:  D SCHWARTZ; J LELLOUCH; R FLAMANT; P F DENOIX
Journal:  Rev Fr Etud Clin Biol       Date:  1962 Jun-Jul

3.  An epidemiological study of cancer of the digestive organs and respiratory system. A study based on 7078 cases.

Authors:  J PERNU
Journal:  Ann Med Intern Fenn Suppl       Date:  1960

4.  Aetiological factors in mouth cancer; an approach to its prevention.

Authors:  E L WYNDER; I J BROSS
Journal:  Br Med J       Date:  1957-05-18

5.  Thickening and contraction of the palmar fascia (Dupuytren's contracture) associated with alcoholism and hepatic cirrhosis.

Authors:  C S DAVIDSON; W H SUMMERSKILL; S J WOLFE
Journal:  N Engl J Med       Date:  1956-09-20       Impact factor: 91.245

Review 6.  Causes of death of alcoholics.

Authors:  W Schmidt; J De Lint
Journal:  Q J Stud Alcohol       Date:  1972-03

7.  A histopathologic study on the effect of alcohol on cirrhosis and hepatoma of autopsy cases in Japan.

Authors:  M Sakurai
Journal:  Acta Pathol Jpn       Date:  1969-08

8.  Cancer of the oesophagus: further evidence of the relation to drinking habits in France.

Authors:  A J Tuyns
Journal:  Int J Cancer       Date:  1970-01-15       Impact factor: 7.396

9.  Oesophageal and lung cancers in Natal African males in relation to certain socio-economic factors. An analysis of 484 interviews.

Authors:  E Bradshaw; M Schonland
Journal:  Br J Cancer       Date:  1969-06       Impact factor: 7.640

10.  Cancer of the oesophagus in Africa. A summary and evaluation of the evidence for the frequency of occurrence, and a preliminary indication of the possible association with the consumption of alcoholic drinks made from maize.

Authors:  P Cook
Journal:  Br J Cancer       Date:  1971-12       Impact factor: 7.640

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