Literature DB >> 21297744

Cardiovascular effects of tricyclic and tetracyclic antidepressants.

C Bilgi, R Campbell.   

Abstract

This article reviews all available studies on the cardiovascular effects of tri- and tetracyclic antidepressants at therapeutic and toxic levels. There is growing evidence that tricyclics, even at therapeutic levels, can be cardiotoxic. Plasma TCA levels are too variable to define a safe therapeutic range. Any patient showing cardiovascular side effects should have an ECG before continuing medication.

Entities:  

Year:  1979        PMID： 21297744      PMCID： PMC2383104     

Source DB:  PubMed          Journal:  Can Fam Physician        ISSN： 0008-350X            Impact factor:   3.275


  32 in total

1.  INHIBITION OF NORADRENALINE UPTAKE BY DRUGS.

Authors:  L L IVERSEN
Journal:  J Pharm Pharmacol       Date:  1965-01       Impact factor: 3.765

2.  AMITRIPTYLINE POISONING.

Authors:  R GOULDING
Journal:  Lancet       Date:  1965-09-04       Impact factor: 79.321

3.  IMIPRAMINE-INDUCED AURICULAR FIBRILLATION.

Authors:  C N MOOREHEAD; S J KNOX
Journal:  Am J Psychiatry       Date:  1965-08       Impact factor: 18.112

4.  Pharmacological studies with tofranil.

Authors:  E B SIGG
Journal:  Can Psychiatr Assoc J       Date:  1959

5.  Hypotension from drugs: incidence, peril, prevention.

Authors:  J W Jefferson
Journal:  Dis Nerv Syst       Date:  1974-02

6.  Survival after imipramine poisoning.

Authors:  I D Ramsay
Journal:  Lancet       Date:  1967-12-16       Impact factor: 79.321

7.  The action of protriptyline on peripheral autonomic function.

Authors:  K D Cairncross; M W McCulloch; F Mitchelson
Journal:  J Pharmacol Exp Ther       Date:  1965-09       Impact factor: 4.030

8.  Amitriptyline and heart block.

Authors:  R B Smith; B J Rusbatch
Journal:  Br Med J       Date:  1967-07-29

9.  On the peripheral pharmacology of amitriptyline.

Authors:  K D Cairncross
Journal:  Arch Int Pharmacodyn Ther       Date:  1965-04

10.  SPECIES DIFFERENCES IN THE METABOLISM OF IMIPRAMINE AND DESMETHYLIMIPRAMINE (DMI).

Authors:  J V DINGELL; F SULSER; J R GILLETTE
Journal:  J Pharmacol Exp Ther       Date:  1964-01       Impact factor: 4.030
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