| Literature DB >> 21297352 |
Motohiro Shiotani1, Kyoko Nakano, Emiko Yamauchi, Yoshiya Oda, Satoru Hosokawa, Toyohiko Aoki.
Abstract
Proteomic analysis was carried out for neuronal vacuolation in rat retrosplenial cortex (RSC) induced by MK-801, a N-methyl-D-aspartate (NMDA) receptor antagonist. Female rats were given a single subcutaneous (sc) injection of either MK-801 (9 mg/kg in saline) or saline. Comparison of changes in proteins in the RSC region between MK-801- and saline-treated groups revealed that MK-801 induced changes in six proteins involved in vesicular transport (vesicle-fusing ATPase) and glycolysis (fructose-bisphosphate aldolase C, triosephosphate isomerase, and glyceraldehyde-3-phosphate dehydrogenase).Entities:
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Year: 2011 PMID： 21297352 DOI： 10.2131/jts.36.131
Source DB: PubMed Journal: J Toxicol Sci ISSN： 0388-1350 Impact factor: 2.196