Literature DB >> 21297323

Intestinal involvement in Wegener's granulomatosis diagnosed and followed up by double balloon enteroscopy.

Kazuko Beppu1, Taro Osada, Kanako Inoue, Kenshi Matsumoto, Tomoyoshi Shibuya, Naoto Sakamoto, Masato Kawabe, Akihito Nagahara, Tatsuo Ogihara, Sumio Watanabe.   

Abstract

Wegener's granulomatosis (WG) is a multisystemic disease of unknown etiology characterized by necrotizing vasculitis and granulomatous inflammation (1-3). The disease typically involves the upper airways, lungs and kidneys, and gastrointestinal involvement is uncommon. Described here is a 33-year-old man who presented at the hospital with abdominal pain. Colonoscopy revealed multiple ulcers, including round ulcers, throughout the large intestine. Small bowel ulcers were detected by double balloon enteroscopy (DBE). Further study confirmed that these ulcers were caused by gastrointestinal complications of WG. The patient was administered prednisolone and cyclophosphamide and remains in remission. This case indicates the importance of considering a gastrointestinal complication of WG as the potential cause of abdominal symptoms among WG patients as well as the use of DBE in detecting such a complication.

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Year:  2011        PMID: 21297323     DOI: 10.2169/internalmedicine.50.4188

Source DB:  PubMed          Journal:  Intern Med        ISSN: 0918-2918            Impact factor:   1.271


  2 in total

1.  Advances in balloon endoscopes.

Authors:  Akihiro Araki; Kiichiro Tsuchiya; Mamoru Watanabe
Journal:  Clin J Gastroenterol       Date:  2014-04-23

2.  Microscopic polyangiitis complicated with ileal involvement detected by double-balloon endoscopy: a case report.

Authors:  Masashi Fukushima; Satoko Inoue; Yuichiro Ono; Yoshitaka Tamaki; Hajime Yoshimura; Yukihiro Imai; Tetsuro Inokuma
Journal:  BMC Gastroenterol       Date:  2013-03-02       Impact factor: 3.067

  2 in total

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