| Literature DB >> 21297097 |
K Watanabe1, M Honda, T Watanabe, K Tsukada, K Teruya, Y Kikuchi, S Oka, H Gatanaga.
Abstract
Integrase inhibitor-resistant HIV-1 was detected in the cerebrospinal fluid, but not in the plasma of a 42-year-old man with HIV encephalopathy treated with a raltegravir (RAL)-containing regimen. Raltegravir resistance may develop in the central nervous system when the virus is already multi-drug resistant because of different penetration into cerebrospinal fluid of individual antiretroviral agents.Entities:
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Year: 2010 PMID： 21297097 DOI： 10.1258/ijsa.2009.009283
Source DB: PubMed Journal: Int J STD AIDS ISSN： 0956-4624 Impact factor: 1.359