Literature DB >> 21296814

Prevalence and risk factors for refractive errors in Indians: the Singapore Indian Eye Study (SINDI).

Chen-Wei Pan1, Tien-Yin Wong, Raghavan Lavanya, Ren-Yi Wu, Ying-Feng Zheng, Xiao-Yu Lin, Paul Mitchell, Tin Aung, Seang-Mei Saw.   

Abstract

PURPOSE: To determine the prevalence and risk factors for refractive errors in middle-aged to elderly Singaporeans of Indian ethnicity.
METHODS: A population-based, cross-sectional study of Indians aged over 40 years of age residing in Southwestern Singapore was conducted. An age-stratified (10-year age group) random sampling procedure was performed to select participants. Refraction was determined by autorefraction followed by subjective refraction. Myopia was defined as spherical equivalent (SE) < -0.50 diopters (D), high myopia as SE < -5.00 D, astigmatism as cylinder < -0.50 D, hyperopia as SE > 0.50 D, and anisometropia as SE difference > 1.00 D. Prevalence was adjusted to the 2000 Singapore census.
RESULTS: Of the 4497 persons eligible to participate, 3400 (75.6%) were examined. Complete data were available for 2805 adults with right eye refractive error and no prior cataract surgery. The age-adjusted prevalence was 28.0% (95% confidence interval [CI], 25.8-30.2) for myopia and 4.1% (95% CI, 3.3-5.0) for high myopia. There was a U-shaped relationship between myopia and increasing age. The age-adjusted prevalence was 54.9% (95% CI, 52.0-57.9) for astigmatism, 35.9% (95% CI, 33.7-38.3) for hyperopia, and 9.8% (95% CI, 8.6-11.1) for anisometropia. In a multiple logistic regression model, adults who were female, younger, taller, spent more time reading and writing per day, or had astigmatism were more likely to be myopic. Adults who were older or had myopia or diabetes mellitus had higher risk of astigmatism.
CONCLUSIONS: In Singapore, the prevalence of myopia in Indian adults is similar to those in Malays, but lower than those in Chinese. Risk factors for myopia are similar across the three ethnic groups in Singapore.

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Year:  2011        PMID: 21296814     DOI: 10.1167/iovs.10-6210

Source DB:  PubMed          Journal:  Invest Ophthalmol Vis Sci        ISSN: 0146-0404            Impact factor:   4.799


  34 in total

1.  Correlation between polymorphisms in the MFN1 gene and myopia in Chinese population.

Authors:  Yun-Chun Zou; Jia-Hong Lei; Ying Wang; Shuang Xu
Journal:  Int J Ophthalmol       Date:  2015-12-18       Impact factor: 1.779

2.  Association of COL1A1 polymorphism with high myopia: a Meta-analysis.

Authors:  Guang-Ming Jin; Xiao-Jing Zhao; Ai-Ming Chen; Yong-Xing Chen; Qin Li
Journal:  Int J Ophthalmol       Date:  2016-04-18       Impact factor: 1.779

3.  Influence of diabetes on macular thickness measured using optical coherence tomography: the Singapore Indian Eye Study.

Authors:  C C A Sng; C Y Cheung; R E Man; W Wong; R Lavanya; P Mitchell; T Aung; T Y Wong
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Review 7.  Genetic susceptibility and mechanisms for refractive error.

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8.  An association study of the COL1A1 gene and high myopia in a Han Chinese population.

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9.  Prevalence and risk factors of refractive error in Qinghai, China: a cross-sectional study in Han and Tibetan adults in Xining and surrounding areas.

Authors:  Meng Wang; Linyang Gan; Jiantao Cui; Guangliang Shan; Ting Chen; Xianghua Wang; Yuhan Wang; Li Pan; Zhanquan Li; Sen Cui; Airong Yang; Wenfang Li; Guoqiang Jia; Ximing Han; Huijing He; Yong Zhong; Jin Ma
Journal:  BMC Ophthalmol       Date:  2021-06-19       Impact factor: 2.209

10.  Muscarinic cholinergic receptor (M2) plays a crucial role in the development of myopia in mice.

Authors:  Veluchamy A Barathi; Jia Lin Kwan; Queenie S W Tan; Sung Rhan Weon; Li Fong Seet; Liang Kee Goh; Eranga N Vithana; Roger W Beuerman
Journal:  Dis Model Mech       Date:  2013-05-02       Impact factor: 5.758

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