Literature DB >> 21295623

Identification of blood microRNAs associated to Parkinsonĭs disease.

Regina Margis1, Rogério Margis, Carlos R M Rieder.   

Abstract

The present study demonstrates that blood samples can be used as a source of miRNA identification associated to Parkinson's disease (PD). A set of six differentially expressed microRNAs were identified. They form two groups according to their expression profile in control, non-treated, early-onset and treated Parkinson's disease subjects. While miR-1, miR-22* and miR-29 expression levels allowed to distinguish non-treated PD from healthy subjects, miR-16-2*, miR-26a2* and miR30a differentiated treated from untreated patients. This study is innovative in contributing to the development of effective PD biomarkers.
Copyright © 2011 Elsevier B.V. All rights reserved.

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Year:  2011        PMID: 21295623     DOI: 10.1016/j.jbiotec.2011.01.023

Source DB:  PubMed          Journal:  J Biotechnol        ISSN: 0168-1656            Impact factor:   3.307


  107 in total

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Review 10.  The roles of non-coding RNAs in Parkinson's disease.

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