Literature DB >> 21295473

Specific biotinylation of IMP dehydrogenase.

B Christopher Hoefler1, Deviprasad R Gollapalli, Lizbeth Hedstrom.   

Abstract

IMP dehydrogenase (IMPDH) catalyzes a critical step in guanine nucleotide biosynthesis. IMPDH also has biological roles that are distinct from its enzymatic function. We report a biotin-linked reagent that selectively labels IMPDH and is released by dithiothreitol. This reagent will be invaluable in elucidating the moonlighting functions of IMPDH.
Copyright © 2011 Elsevier Ltd. All rights reserved.

Entities:  

Mesh：

Substances：

Year:  2011        PMID： 21295473      PMCID： PMC3044611          DOI： 10.1016/j.bmcl.2011.01.042

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN： 0960-894X            Impact factor:   2.823


  15 in total

1.  REACTIONS OF RIBONUCLEOTIDE DERIVATIVES OF PURINE ANALOGUES AT THE CATALYTIC SITE OF INOSINE 5'-PHOSPHATE DEHYDROGENASE.

Authors:  A HAMPTON
Journal:  J Biol Chem       Date:  1963-09       Impact factor: 5.157

2.  Inactivation of guanosine 5'-phosphate reductase by 6-chloro-, 6-mercapto-, and 2-amino-6-mercapto-9-beta-D-ribofuranosylpurine 5'-phosphates.

Authors:  L W Brox; A Hampton
Journal:  Biochemistry       Date:  1968-01       Impact factor: 3.162

3.  Inosine 5'-phosphate dehydrogenase. Site of inhibition by guanosine 5'-phosphate and of inactivation by 6-chloro- and 6-mercaptopurine ribonucleoside 5'-phosphates.

Authors:  A Hampton; A Nomura
Journal:  Biochemistry       Date:  1967-03       Impact factor: 3.162

4.  Crystal structure of human type II inosine monophosphate dehydrogenase: implications for ligand binding and drug design.

Authors:  T D Colby; K Vanderveen; M D Strickler; G D Markham; B M Goldstein
Journal:  Proc Natl Acad Sci U S A       Date:  1999-03-30       Impact factor: 11.205

5.  Autosomal dominant retinitis pigmentosa mutations in inosine 5'-monophosphate dehydrogenase type I disrupt nucleic acid binding.

Authors:  Sarah E Mortimer; Lizbeth Hedstrom
Journal:  Biochem J       Date:  2005-08-15       Impact factor: 3.857

6.  Active-site modification of native and mutant forms of inosine 5'-monophosphate dehydrogenase from Escherichia coli K12.

Authors:  H J Gilbert; W T Drabble
Journal:  Biochem J       Date:  1980-11-01       Impact factor: 3.857

7.  Participation of yeast inosine 5'-monophosphate dehydrogenase in an in vitro complex with a fragment of the C-rich telomeric strand.

Authors:  Jean François Cornuel; Anne Moraillon; Maurice Guéron
Journal:  Biochimie       Date:  2002-04       Impact factor: 4.079

8.  IMP dehydrogenase is recruited to the transcription complex through serine 2 phosphorylation of RNA polymerase II.

Authors:  Jae-Hyun Park; Seong Hoon Ahn
Journal:  Biochem Biophys Res Commun       Date:  2010-01-25       Impact factor: 3.575

9.  Identification of the IMP binding site in the IMP dehydrogenase from Tritrichomonas foetus.

Authors:  J A Huete-Pérez; J C Wu; F G Whitby; C C Wang
Journal:  Biochemistry       Date:  1995-10-24       Impact factor: 3.162

10.  Probing the active site of human IMP dehydrogenase using halogenated purine riboside 5'-monophosphates and covalent modification reagents.

Authors:  L C Antonino; K Straub; J C Wu
Journal:  Biochemistry       Date:  1994-02-22       Impact factor: 3.162
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.