Literature DB >> 21295378

Replication analysis of SNPs on 9p21.2 and 19p13.3 with amyotrophic lateral sclerosis in East Asians.

Aritoshi Iida1, Atsushi Takahashi, Min Deng, Yun Zhang, Jing Wang, Naoki Atsuta, Fumiaki Tanaka, Tetsumasa Kamei, Motoki Sano, Shuichi Oshima, Torao Tokuda, Mitsuya Morita, Chizuru Akimoto, Masahiro Nakajima, Michiaki Kubo, Naoyuki Kamatani, Imaharu Nakano, Gen Sobue, Yusuke Nakamura, Dongsheng Fan, Shiro Ikegawa.   

Abstract

We performed a replication study of the 2 genetic variants, rs2814707 on 9p21.2 and rs12608932 on 19p13.3 that are recently reported to be most significantly associated with sporadic amyotrophic lateral sclerosis (ALS) in Caucasians. Both rs12608932 and rs2814707 showed no evidence of association in Japanese and Chinese (rs12608932, combined p = 0.58, odds ratio [OR] = 1.03, 95% confidence interval [CI] 0.93-1.13; rs2814707, combined p = 0.88, OR = 1.10, 95% CI 0.93-1.30). The association of these loci with susceptibility to sporadic ALS is considered negative in East Asians.
Copyright © 2011 Elsevier Inc. All rights reserved.

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Year:  2011        PMID： 21295378     DOI： 10.1016/j.neurobiolaging.2010.12.011

Source DB:  PubMed          Journal:  Neurobiol Aging        ISSN： 0197-4580            Impact factor:   4.673


  7 in total

1.  UNC13A variant rs12608932 is associated with increased risk of amyotrophic lateral sclerosis and reduced patient survival: a meta-analysis.

Authors:  Baiyuan Yang; Haixia Jiang; Fang Wang; Shimei Li; Chongmin Wu; Jianjian Bao; Yongyun Zhu; Zhong Xu; Bin Liu; Hui Ren; Xinglong Yang
Journal:  Neurol Sci       Date:  2019-06-14       Impact factor: 3.307

Review 2.  Making connections: pathology and genetics link amyotrophic lateral sclerosis with frontotemporal lobe dementia.

Authors:  Faisal Fecto; Teepu Siddique
Journal:  J Mol Neurosci       Date:  2011-09-07       Impact factor: 3.444

3.  UNC13A confers risk for sporadic ALS and influences survival in a Spanish cohort.

Authors:  Jose Manuel Vidal-Taboada; Alan Lopez-Lopez; Maria Salvado; Laura Lorenzo; Cecilia Garcia; Nicole Mahy; Manuel J Rodríguez; Josep Gamez
Journal:  J Neurol       Date:  2015-07-11       Impact factor: 4.849

4.  Association analysis of four candidate genetic variants with sporadic amyotrophic lateral sclerosis in a Chinese population.

Authors:  Xueping Chen; Rui Huang; Yongping Chen; Zhenzhen Zheng; Ke Chen; Wei Song; Bi Zhao; Yuan Yang; Lixing Yuan; Huifang Shang
Journal:  Neurol Sci       Date:  2014-02-04       Impact factor: 3.307

5.  A genome-wide association meta-analysis identifies a novel locus at 17q11.2 associated with sporadic amyotrophic lateral sclerosis.

Authors:  Isabella Fogh; Antonia Ratti; Cinzia Gellera; Kuang Lin; Cinzia Tiloca; Valentina Moskvina; Lucia Corrado; Gianni Sorarù; Cristina Cereda; Stefania Corti; Davide Gentilini; Daniela Calini; Barbara Castellotti; Letizia Mazzini; Giorgia Querin; Stella Gagliardi; Roberto Del Bo; Francesca L Conforti; Gabriele Siciliano; Maurizio Inghilleri; Francesco Saccà; Paolo Bongioanni; Silvana Penco; Massimo Corbo; Sandro Sorbi; Massimiliano Filosto; Alessandra Ferlini; Anna M Di Blasio; Stefano Signorini; Aleksey Shatunov; Ashley Jones; Pamela J Shaw; Karen E Morrison; Anne E Farmer; Philip Van Damme; Wim Robberecht; Adriano Chiò; Bryan J Traynor; Michael Sendtner; Judith Melki; Vincent Meininger; Orla Hardiman; Peter M Andersen; Nigel P Leigh; Jonathan D Glass; Daniel Overste; Frank P Diekstra; Jan H Veldink; Michael A van Es; Christopher E Shaw; Michael E Weale; Cathryn M Lewis; Julie Williams; Robert H Brown; John E Landers; Nicola Ticozzi; Mauro Ceroni; Elena Pegoraro; Giacomo P Comi; Sandra D'Alfonso; Leonard H van den Berg; Franco Taroni; Ammar Al-Chalabi; John Powell; Vincenzo Silani
Journal:  Hum Mol Genet       Date:  2013-11-20       Impact factor: 6.150

6.  The clinical assessment of amyotrophic lateral sclerosis patients' prognosis by ZNF512B gene, neck flexor muscle power score and body mass index (BMI).

Authors:  Chun-Jiang Yu; Li Wang; Sen-Lin Mao; Ying Zhang; Ling-Ling Song; Ling-Yu Cai; Ye Tao
Journal:  BMC Neurol       Date:  2018-12-19       Impact factor: 2.474

7.  Single-nucleotide Polymorphism rs2275294 in ZNF512B is not Associated with Susceptibility to Amyotrophic Lateral Sclerosis in a Large Chinese Cohort.

Authors:  Xiao-Dong Ju; Tao Liu; Jing Chen; Xiao-Gang Li; Xin-Xiu Liu; Wen-Chao Liu; Kai Wang; Min Deng
Journal:  Chin Med J (Engl)       Date:  2015-12-20       Impact factor: 2.628
  7 in total

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