Literature DB >> 21295224

Subjective quality of life in patients with chronic schizophrenia: relationships between psychosocial and clinical characteristics.

Yu-Chen Kao1, Yia-Ping Liu, Ming-Kuen Chou, Tsung-Hsing Cheng.   

Abstract

BACKGROUND: Using the theoretical framework of quality of life (QOL), many studies have demonstrated that the beliefs individuals hold about their QOL are important in predicting health outcomes. This study tested the Taiwanese version of the World Health Organization Quality of Life-Brief (WHOQOL-BREF) assessment in schizophrenia patients. The WHOQOL-BREF is a cross-cultural and widely used measure for assessing health-related QOL. This brief version of the questionnaire derived from the concepts included in the 100-item WHOQOL questionnaire was adapted for use in Taiwan.
METHODS: In the current cross-sectional study, 104 patients who met Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition criteria for schizophrenia or schizoaffective disorder according to Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition criteria were recruited and independently interviewed using the Taiwanese version of the WHOQOL-BREF. Patients were also examined using various other scales assessing insight, symptom severity, general psychopathology, and antipsychotic-induced side effects. In addition, we analyzed demographic data, clinical variables, and several self-rating scales as correlates of the Taiwanese version of the WHOQOL-BREF.
RESULTS: As predicted, age, onset of illness, insight measures, symptom severity, general psychopathology, and antipsychotic-induced side effects were all significantly related to the QOL scores. Multiple regression analyses revealed that depressive symptoms, antipsychotic-induced parkinsonism side effects, hopelessness, and age at illness onset were the 4 strongest predictors of subjective QOL in schizophrenia patients. These variables accounted for 39.2% of the total variance of this QOL model.
CONCLUSIONS: The results suggest that the WHOQOL-BREF is a promising model for mental assessing health problems in schizophrenia patients. Furthermore, the present findings highlight the importance of understanding the complex nature of the concept of QOL. Our study also supports the belief that different domains of QOL are likely to have different predictors.
Copyright © 2011 Elsevier Inc. All rights reserved.

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Year:  2010        PMID: 21295224     DOI: 10.1016/j.comppsych.2010.05.008

Source DB:  PubMed          Journal:  Compr Psychiatry        ISSN: 0010-440X            Impact factor:   3.735


  15 in total

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2.  The impact of cognitive insight, self-stigma, and medication compliance on the quality of life in patients with schizophrenia.

Authors:  Yin-Ju Lien; Hsin-An Chang; Yu-Chen Kao; Nian-Sheng Tzeng; Chien-Wen Lu; Ching-Hui Loh
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3.  Quality of life and adverse effects of olanzapine versus risperidone therapy in patients with schizophrenia.

Authors:  Katarina Melo Chaves; Antoni Serrano-Blanco; Susana Barbosa Ribeiro; Luiz Alberto Lira Soares; Gerlane Coelho Bernardo Guerra; Maria do Socorro Costa Feitosa Alves; Raimundo Fernandes de Araújo Júnior; Vanessa de Paula Soares Rachetti; Antônio Filgueira Júnior; Aurigena Antunes de Araújo
Journal:  Psychiatr Q       Date:  2013-03

4.  Symptomatic Remission Determines Functional Improvement and Quality of Life in Schizophrenia.

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Authors:  V O Lasebikan; E T Owoaje
Journal:  Community Ment Health J       Date:  2015-02-21

6.  Telemedical care and quality of life in patients with schizophrenia and bipolar disorder: results of a randomized controlled trial.

Authors:  Ulrike Stentzel; Neeltje van den Berg; Kilson Moon; Lara N Schulze; Josephine Schulte; Jens M Langosch; Wolfgang Hoffmann; Hans J Grabe
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8.  Health-related quality of life in patients with dual diagnosis: clinical correlates.

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Journal:  Health Qual Life Outcomes       Date:  2012-09-05       Impact factor: 3.186

9.  Factors Affecting Well-being and Socio-occupational Functioning in Schizophrenia Patients Following an Acute Exacerbation: A Hospital Based Observational Study.

Authors:  Roopa Gopalakrishnan; Rishikesh V Behere; P S V N Sharma
Journal:  Indian J Psychol Med       Date:  2015 Oct-Dec

10.  Relationship of quality of life with disability grade in obsessive compulsive disorder and dysthymic disorder.

Authors:  Nv Roopesh Gopal; Cy Sudarshan; S Ganesh Kumar
Journal:  Indian J Palliat Care       Date:  2014-09
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