| Literature DB >> 21295153 |
Sophie A Valkenburg1, John A Rutigliano, Ali H Ellebedy, Peter C Doherty, Paul G Thomas, Katherine Kedzierska.
Abstract
The introduction of a new influenza strain into human circulation leads to rapid global spread. This review summarizes innate and adaptive immunity to influenza viruses, with an emphasis on T-cell responses that provide cross-protection between distinct subtypes and strains. We discuss antigenic variation within T-cell immunogenic peptides and our understanding of pre-existing immunity towards the pandemic A(H1N1) 2009 strain.Entities:
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Year: 2011 PMID: 21295153 PMCID: PMC3549300 DOI: 10.1016/j.micinf.2011.01.007
Source DB: PubMed Journal: Microbes Infect ISSN: 1286-4579 Impact factor: 2.700