| Literature DB >> 21295133 |
Maged M Harraz1, Ted M Dawson, Valina L Dawson.
Abstract
MicroRNAs are small non-protein coding RNAs that regulate gene expression through post-transcriptional repression. Recent studies demonstrated the importance of microRNAs in the nervous system development, function and disease. Parkinson's disease is the second most prevalent neurodegenerative disease with only symptomatic treatment available. Recent success in using small RNAs as therapeutic targets hold a substantial promise for the Parkinson's disease field. Here we review recent work linking the microRNA pathway to Parkinson's disease.Entities:
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Year: 2011 PMID： 21295133 PMCID： PMC3163813 DOI： 10.1016/j.jchemneu.2011.01.005
Source DB: PubMed Journal: J Chem Neuroanat ISSN： 0891-0618 Impact factor: 3.052