OBJECTIVES: Infectious intestinal diseases cause substantial morbidity and economic loss in the UK. Rotavirus gastroenteritis (RVGE), a form of gastroenteritis, is the primary cause of severe diarrhoea in children. The primary objective of this study was to examine whether hospitalisation for gastroenteritis, and particularly RVGE, is linked to social deprivation. METHODS: A retrospective study relating to hospital admissions in England with rotavirus, gastroenteritis, or type 1 diabetes mellitus (T1DM) was conducted in children aged under 5 years between 1st April 2009 and 31st March 2010 using the CHKS database. Admissions with selected diagnoses were extracted based on ICD-10 coding. Deprivation data were obtained from the Index of Multiple Deprivation (IMD) 2007 for England. RESULTS: A total of 20,571 unique hospital admissions were made by children, in England, with RVGE (n = 1334; 6.5%) together with a diagnosis of infectious gastroenteritis of all causes (n = 19,237; 93.5%), giving an overall hospital admission rate, for those aged under 5 years, of 65.7 per 10,000 population. With 'rank of average score' and the 'rank of average rank' as measures of deprivation, the rate of hospital admissions with gastroenteritis of all causes decreased by 0.346 and 0.287 per 10,000 (p < 0.001) respectively for every unit increase in deprivation rank (decreasing deprivation), though this trend was not observed in patients admitted with RVGE specifically. CONCLUSIONS: Hospital admissions with gastroenteritis of all causes increased as deprivation increased. The implementation of a rotavirus vaccination programme would help to reduce the burden of RVGE and gastroenteritis of all causes, and in the context of gastroenteritis, some elements of health and social inequality may be vaccine preventable. LIMITATIONS: It is possible that the study is limited by the accuracy and completeness of deprivation indices, and coding within CHKS; the existence of the 'ecological fallacy' must also be considered.
OBJECTIVES: Infectious intestinal diseases cause substantial morbidity and economic loss in the UK. Rotavirus gastroenteritis (RVGE), a form of gastroenteritis, is the primary cause of severe diarrhoea in children. The primary objective of this study was to examine whether hospitalisation for gastroenteritis, and particularly RVGE, is linked to social deprivation. METHODS: A retrospective study relating to hospital admissions in England with rotavirus, gastroenteritis, or type 1 diabetes mellitus (T1DM) was conducted in children aged under 5 years between 1st April 2009 and 31st March 2010 using the CHKS database. Admissions with selected diagnoses were extracted based on ICD-10 coding. Deprivation data were obtained from the Index of Multiple Deprivation (IMD) 2007 for England. RESULTS: A total of 20,571 unique hospital admissions were made by children, in England, with RVGE (n = 1334; 6.5%) together with a diagnosis of infectious gastroenteritis of all causes (n = 19,237; 93.5%), giving an overall hospital admission rate, for those aged under 5 years, of 65.7 per 10,000 population. With 'rank of average score' and the 'rank of average rank' as measures of deprivation, the rate of hospital admissions with gastroenteritis of all causes decreased by 0.346 and 0.287 per 10,000 (p < 0.001) respectively for every unit increase in deprivation rank (decreasing deprivation), though this trend was not observed in patients admitted with RVGE specifically. CONCLUSIONS: Hospital admissions with gastroenteritis of all causes increased as deprivation increased. The implementation of a rotavirus vaccination programme would help to reduce the burden of RVGE and gastroenteritis of all causes, and in the context of gastroenteritis, some elements of health and social inequality may be vaccine preventable. LIMITATIONS: It is possible that the study is limited by the accuracy and completeness of deprivation indices, and coding within CHKS; the existence of the 'ecological fallacy' must also be considered.
Authors: Melissa N Poulsen; Jonathan Pollak; Deborah L Sills; Joan A Casey; Sara G Rasmussen; Keeve E Nachman; Sara E Cosgrove; Dalton Stewart; Brian S Schwartz Journal: Int J Hyg Environ Health Date: 2017-12-15 Impact factor: 5.840
Authors: Suzanne Spence; Jennifer Delve; Elaine Stamp; John N S Matthews; Martin White; Ashley J Adamson Journal: PLoS One Date: 2014-11-19 Impact factor: 3.240
Authors: Natalie L Adams; Tanith C Rose; Jeremy Hawker; Mara Violato; Sarah J O'Brien; Benjamin Barr; Victoria J K Howard; Margaret Whitehead; Ross Harris; David C Taylor-Robinson Journal: PLoS One Date: 2018-01-23 Impact factor: 3.240
Authors: Daniel Hungerford; Roberto Vivancos; Jonathan M Read; Miren Iturriza-Gόmara; Neil French; Nigel A Cunliffe Journal: BMC Med Date: 2018-01-29 Impact factor: 8.775
Authors: Tanith C Rose; Natalie Adams; David C Taylor-Robinson; Benjamin Barr; Jeremy Hawker; Sarah O'Brien; Mara Violato; Margaret Whitehead Journal: Syst Rev Date: 2016-01-21