Literature DB >> 21293783

Penetrating atherosclerotic aortic ulcer.

Ryan Walsh1, Brooks Laselle, Peter Stull.   

Abstract

Entities:  

Year:  2010        PMID: 21293783      PMCID: PMC3027456     

Source DB:  PubMed          Journal:  West J Emerg Med        ISSN: 1936-900X


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A 79-year-old female presented to the emergency department complaining of two weeks of dyspnea on exertion and heart palpitations. A computed tomography (CT) pulmonary angiogram was obtained to rule out pulmonary embolism, which was negative. An incidental finding of a penetrating atherosclerotic ulcer (PAU) of the descending aorta was reported (Figure 1). A focused bedside ultrasound of this structure was then performed (Figure 2).
Figure 1

Computed tomography image depicting the lesion in the descending aorta.

Figure 2

Ultrasound image of the proximal abdominal aorta.

This patient was admitted to the hospital with a vascular surgery consultation and managed with blood pressure control. She was discharged home after a negative work-up for her dyspnea with vascular surgery follow up.

DISCUSSION

PAU occurs due to ulceration of the intima layer of the aorta leading to exposure of the media. Up to 20% of patients will be asymptomatic on presentation; however, most patients complain of anterior chest or midscapular back pain.1 PAU is uniformly associated with hypertension and presents between the seventh and ninth decades of life.2 Ultrasound findings of PAU are based largely upon transesophageal echocardiography describing an asymmetric out pouching of the aortic wall with jagged edges and no intimal flap.3 In our experience the findings on bedside abdominal ultrasound of a descending PAU are similar to saccular aortic aneurysms and CT is helpful in differentiating these conditions. We believe this is the first description of PAU on bedside abdominal ultrasound in the literature. Management of ascending PAU is emergent surgical repair while descending PAU can be managed with tight blood pressure control and repeat imaging. PAU is a rare but serious clinical entity. While the rate of rupture is as high as 40% in one series of symptomatic patients, many reports suggest a much lower rate when PAU is an incidental diagnosis.4 The views expressed herein are solely those of the authors and do not represent the official views of the Department of Defense or Army Medical Department.
  4 in total

1.  Penetrating atherosclerotic ulcer of the aorta: imaging features and disease concept.

Authors:  H Hayashi; Y Matsuoka; I Sakamoto; E Sueyoshi; T Okimoto; K Hayashi; N Matsunaga
Journal:  Radiographics       Date:  2000 Jul-Aug       Impact factor: 5.333

2.  Pathologic variants of thoracic aortic dissections. Penetrating atherosclerotic ulcers and intramural hematomas.

Authors:  M A Coady; J A Rizzo; J A Elefteriades
Journal:  Cardiol Clin       Date:  1999-11       Impact factor: 2.213

Review 3.  Echocardiography in the emergency assessment of acute aortic syndromes.

Authors:  E Louise Meredith; Navroz D Masani
Journal:  Eur J Echocardiogr       Date:  2009-01

4.  Penetrating ulcer of the thoracic aorta: what is it? How do we recognize it? How do we manage it?

Authors:  M A Coady; J A Rizzo; G L Hammond; J G Pierce; G S Kopf; J A Elefteriades
Journal:  J Vasc Surg       Date:  1998-06       Impact factor: 4.268

  4 in total
  1 in total

1.  Penetrating Aortic Ulceration With Pseudoaneurysm and Intramural Hematoma: Emergency Department Management and Point-of-Care Ultrasound Diagnosis.

Authors:  Derrick Huang; Alexander Huttleston; Frank Fraunfelter; Leoh N Leon; Latha Ganti
Journal:  Cureus       Date:  2022-07-31
  1 in total

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