Literature DB >> 21293505

GERD in 2010: diagnosis, novel mechanisms of disease and promising agents.

Arne Kandulski1, Peter Malfertheiner.   

Abstract

The results of various studies from 2010 have underlined the importance of the careful diagnostic assessment of GERD. Recent studies have also provided further evidence of the complex pathogenesis of GERD, and promising agents targeting the underlying factors in the pathogenesis of this condition are in the pipeline, especially for treatment-refractory GERD.

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Year:  2011        PMID： 21293505     DOI： 10.1038/nrgastro.2010.220

Source DB:  PubMed          Journal:  Nat Rev Gastroenterol Hepatol        ISSN： 1759-5045            Impact factor:   46.802


  10 in total

1.  Effects of lesogaberan on reflux and lower esophageal sphincter function in patients with gastroesophageal reflux disease.

Authors:  Guy E Boeckxstaens; Hanneke Beaumont; Veerle Mertens; Hans Denison; Magnus Ruth; John Adler; Debra G Silberg; Daniel Sifrim
Journal:  Gastroenterology       Date:  2010-05-05       Impact factor: 22.682

2.  Increased TRPV1 gene expression in esophageal mucosa of patients with non-erosive and erosive reflux disease.

Authors:  M P L Guarino; L Cheng; J Ma; K Harnett; P Biancani; A Altomare; F Panzera; J Behar; M Cicala
Journal:  Neurogastroenterol Motil       Date:  2010-05-06       Impact factor: 3.598

3.  Characteristics of reflux episodes and symptom association in patients with erosive esophagitis and nonerosive reflux disease: study using combined impedance-pH off therapy.

Authors:  Edoardo Savarino; Radu Tutuian; Patrizia Zentilin; Pietro Dulbecco; Daniel Pohl; Elisa Marabotto; Andrea Parodi; Giorgio Sammito; Lorenzo Gemignani; Giorgia Bodini; Vincenzo Savarino
Journal:  Am J Gastroenterol       Date:  2009-12-08       Impact factor: 10.864

4.  Proteinase-activated receptor-2 in the pathogenesis of gastroesophageal reflux disease.

Authors:  Arne Kandulski; Thomas Wex; Klaus Mönkemüller; Doerthe Kuester; Lucia C Fry; Albert Roessner; Peter Malfertheiner
Journal:  Am J Gastroenterol       Date:  2010-06-29       Impact factor: 10.864

5.  Efficacy, tolerability and pharmacokinetics of a modified release formulation of ADX10059, a negative allosteric modulator of metabotropic glutamate receptor 5: an esophageal pH-impedance study in healthy subjects.

Authors:  F Zerbib; C Keywood; G Strabach
Journal:  Neurogastroenterol Motil       Date:  2010-03-16       Impact factor: 3.598

6.  The impact of pre-endoscopy proton pump inhibitor use on the classification of non-erosive reflux disease and erosive oesophagitis.

Authors:  S Gaddam; S Wani; H Ahmed; P Maddur; S B Hall; N Gupta; S R Puli; A Higbee; A Rastogi; A Bansal; P Sharma
Journal:  Aliment Pharmacol Ther       Date:  2010-09-29       Impact factor: 8.171

7.  Long-term outcome of microscopic esophagitis in chronic GERD patients treated with esomeprazole or laparoscopic antireflux surgery in the LOTUS trial.

Authors:  Roberto Fiocca; Luca Mastracci; Cecilia Engström; Stephen Attwood; Christian Ell; Jean-Paul Galmiche; Jan Hatlebakk; Ola Junghard; Tore Lind; Lars Lundell
Journal:  Am J Gastroenterol       Date:  2009-11-10       Impact factor: 10.864

8.  Acid and weakly acidic solutions impair mucosal integrity of distal exposed and proximal non-exposed human oesophagus.

Authors:  Ricard Farré; Fernando Fornari; Kathleen Blondeau; Michael Vieth; Rita De Vos; Raf Bisschops; Veerle Mertens; Ans Pauwels; Jan Tack; Daniel Sifrim
Journal:  Gut       Date:  2009-11-01       Impact factor: 23.059

9.  Arbaclofen placarbil decreases postprandial reflux in patients with gastroesophageal reflux disease.

Authors:  Lauren B Gerson; F Jacob Huff; Amine Hila; William K Hirota; Sandra Reilley; Amit Agrawal; Ritu Lal; Wendy Luo; Donald Castell
Journal:  Am J Gastroenterol       Date:  2009-12-29       Impact factor: 10.864

10.  Development of consensus guidelines for the histologic recognition of microscopic esophagitis in patients with gastroesophageal reflux disease: the Esohisto project.

Authors:  Roberto Fiocca; Luca Mastracci; Robert Riddell; Kaiyo Takubo; Michael Vieth; Lisa Yerian; Prateek Sharma; Paula Fernström; Magnus Ruth
Journal:  Hum Pathol       Date:  2009-10-01       Impact factor: 3.466
  10 in total
  1 in total

1.  Necrotizing sialometaplasia-like change of the esophageal submucosal glands is associated with Barrett's esophagus.

Authors:  David R Braxton; Dana C Nickleach; Yuan Liu; Alton B Farris
Journal:  Virchows Arch       Date:  2014-05-27       Impact factor: 4.064
  1 in total

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