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Literature DB >> 21290045

High-speed droplet generation on demand driven by pulse laser-induced cavitation.

Sung-Yong Park¹, Ting-Hsiang Wu, Yue Chen, Michael A Teitell, Pei-Yu Chiou.

Abstract

We report on a pulse laser-driven droplet generation (PLDG) mechanism that enables on-demand droplet generation at rates up to 10,000 droplets per second in a single-layer PDMS-based microfluidic device. Injected droplet volumes can be continuously tuned between 1 pL and 150 pL with less than 1% volume variation. This journal is © The Royal Society of Chemistry 2011

Entities: Chemical Disease Species

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Year: 2011 PMID： 21290045 PMCID： PMC3967743 DOI： 10.1039/c0lc00555j

Source DB: PubMed Journal: Lab Chip ISSN： 1473-0189 Impact factor: 6.799

17 in total

Review 1. Fabrication of microfluidic systems in poly(dimethylsiloxane).

Authors: J C McDonald; D C Duffy; J R Anderson; D T Chiu; H Wu; O J Schueller; G M Whitesides
Journal: Electrophoresis Date: 2000-01 Impact factor: 3.535

2. Laser-induced breakdown in large transparent water droplets.

Authors: R K Chang; J H Eickmans; W F Hsieh; C F Wood; J Z Zhang; J B Zheng
Journal: Appl Opt Date: 1988-06-15 Impact factor: 1.980

3. Alternating droplet generation and controlled dynamic droplet fusion in microfluidic device for CdS nanoparticle synthesis.

Authors: Lung-Hsin Hung; Kyung M Choi; Wei-Yu Tseng; Yung-Chieh Tan; Kenneth J Shea; Abraham Phillip Lee
Journal: Lab Chip Date: 2006-01-05 Impact factor: 6.799

4. Microvalve-actuated precise control of individual droplets in microfluidic devices.

Authors: Shaojiang Zeng; Bowei Li; Xiao'ou Su; Jianhua Qin; Bingcheng Lin
Journal: Lab Chip Date: 2009-03-27 Impact factor: 6.799

5. Laser-induced cavitation based micropump.

Authors: Rory Dijkink; Claus-Dieter Ohl
Journal: Lab Chip Date: 2008-08-28 Impact factor: 6.799

6. All-electronic droplet generation on-chip with real-time feedback control for EWOD digital microfluidics.

Authors: Jian Gong; Chang-Jin C J Kim
Journal: Lab Chip Date: 2008-04-21 Impact factor: 6.799

7. Multi-step microfluidic polymerization reactions conducted in droplets: the internal trigger approach.

Authors: Wei Li; Hung H Pham; Zhihong Nie; Brendan MacDonald; Axel Güenther; Eugenia Kumacheva
Journal: J Am Chem Soc Date: 2008-07-02 Impact factor: 15.419

8. Controlling nonspecific protein adsorption in a plug-based microfluidic system by controlling interfacial chemistry using fluorous-phase surfactants.

Authors: L Spencer Roach; Helen Song; Rustem F Ismagilov
Journal: Anal Chem Date: 2005-02-01 Impact factor: 6.986

9. Droplet microfluidic technology for single-cell high-throughput screening.

Authors: Eric Brouzes; Martina Medkova; Neal Savenelli; Dave Marran; Mariusz Twardowski; J Brian Hutchison; Jonathan M Rothberg; Darren R Link; Norbert Perrimon; Michael L Samuels
Journal: Proc Natl Acad Sci U S A Date: 2009-07-15 Impact factor: 11.205

10. Droplet-based microfluidic platforms for the encapsulation and screening of Mammalian cells and multicellular organisms.

Authors: Jenifer Clausell-Tormos; Diana Lieber; Jean-Christophe Baret; Abdeslam El-Harrak; Oliver J Miller; Lucas Frenz; Joshua Blouwolff; Katherine J Humphry; Sarah Köster; Honey Duan; Christian Holtze; David A Weitz; Andrew D Griffiths; Christoph A Merten
Journal: Chem Biol Date: 2008-05

22 in total

High-speed droplet generation on demand driven by pulse laser-induced cavitation.

Review 1. Fabrication of microfluidic systems in poly(dimethylsiloxane).

2. Laser-induced breakdown in large transparent water droplets.

3. Alternating droplet generation and controlled dynamic droplet fusion in microfluidic device for CdS nanoparticle synthesis.

4. Microvalve-actuated precise control of individual droplets in microfluidic devices.

5. Laser-induced cavitation based micropump.

6. All-electronic droplet generation on-chip with real-time feedback control for EWOD digital microfluidics.

7. Multi-step microfluidic polymerization reactions conducted in droplets: the internal trigger approach.

8. Controlling nonspecific protein adsorption in a plug-based microfluidic system by controlling interfacial chemistry using fluorous-phase surfactants.

9. Droplet microfluidic technology for single-cell high-throughput screening.

10. Droplet-based microfluidic platforms for the encapsulation and screening of Mammalian cells and multicellular organisms.

1. Novel on-demand droplet generation for selective fluid sample extraction.

2. Functional TCR T cell screening using single-cell droplet microfluidics.

Review 3. Droplet microfluidics for high-sensitivity and high-throughput detection and screening of disease biomarkers.

4. Optofluidic microvalve-on-a-chip with a surface plasmon-enhanced fiber optic microheater.

5. On demand nanoliter-scale microfluidic droplet generation, injection, and mixing using a passive microfluidic device.

6. Fast-responsive hydrogel as an injectable pump for rapid on-demand fluidic flow control.

7. Pulsed laser triggered high speed microfluidic fluorescence activated cell sorter.

8. On-demand generation and mixing of liquid-in-gas slugs with digitally-programmable composition and size.

Review 9. Micro total analysis systems for cell biology and biochemical assays.

Review 10. Fundamentals of Laser-Based Hydrogel Degradation and Applications in Cell and Tissue Engineering.