Literature DB >> 21289650

Location, location, location: a crystal-clear view of autotaxin saturating LPA receptors.

Adel Tabchy1, Gabor Tigyi, Gordon B Mills.   

Abstract

The interaction of autotaxin with its substrates leads to the production of lysophosphatidic acids (LPA), bioactive lipids with an emerging prominent role in inflammation and cancer. Two papers in this issue tell the previously unknown story of autotaxin, from substrate discrimination to highly efficient local delivery of LPA to target receptors.

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Year:  2011        PMID： 21289650      PMCID： PMC3584164          DOI： 10.1038/nsmb0211-117

Source DB:  PubMed          Journal:  Nat Struct Mol Biol        ISSN： 1545-9985            Impact factor:   15.369


  9 in total

1.  Inhibition of autotaxin by lysophosphatidic acid and sphingosine 1-phosphate.

Authors:  Laurens A van Meeteren; Paula Ruurs; Evangelos Christodoulou; James W Goding; Hideo Takakusa; Kazuya Kikuchi; Anastassis Perrakis; Tetsuo Nagano; Wouter H Moolenaar
Journal:  J Biol Chem       Date:  2005-03-15       Impact factor: 5.157

2.  Crystal structure of autotaxin and insight into GPCR activation by lipid mediators.

Authors:  Hiroshi Nishimasu; Shinichi Okudaira; Kotaro Hama; Emiko Mihara; Naoshi Dohmae; Asuka Inoue; Ryuichiro Ishitani; Junichi Takagi; Junken Aoki; Osamu Nureki
Journal:  Nat Struct Mol Biol       Date:  2011-01-16       Impact factor: 15.369

3.  Structural and functional analysis of the plasminogen activator inhibitor-1 binding motif in the somatomedin B domain of vitronectin.

Authors:  G Deng; G Royle; S Wang; K Crain; D J Loskutoff
Journal:  J Biol Chem       Date:  1996-05-31       Impact factor: 5.157

Review 4.  The emerging role of lysophosphatidic acid in cancer.

Authors:  Gordon B Mills; Wouter H Moolenaar
Journal:  Nat Rev Cancer       Date:  2003-08       Impact factor: 60.716

5.  Autotaxin/lysopholipase D and lysophosphatidic acid regulate murine hemostasis and thrombosis.

Authors:  Zehra Pamuklar; Lorenzo Federico; Shuying Liu; Makiko Umezu-Goto; Anping Dong; Manikandan Panchatcharam; Zachary Fulkerson; Zachary Fulerson; Evgeny Berdyshev; Viswanathan Natarajan; Xianjun Fang; Laurens A van Meeteren; Wouter H Moolenaar; Gordon B Mills; Andrew J Morris; Susan S Smyth
Journal:  J Biol Chem       Date:  2009-01-12       Impact factor: 5.157

6.  Domain interplay mediated by an essential disulfide linkage is critical for the activity and secretion of the metastasis-promoting enzyme autotaxin.

Authors:  Silvia Jansen; Maria Andries; Rita Derua; Etienne Waelkens; Mathieu Bollen
Journal:  J Biol Chem       Date:  2009-03-27       Impact factor: 5.157

7.  Identification, purification, and partial sequence analysis of autotaxin, a novel motility-stimulating protein.

Authors:  M L Stracke; H C Krutzsch; E J Unsworth; A Arestad; V Cioce; E Schiffmann; L A Liotta
Journal:  J Biol Chem       Date:  1992-02-05       Impact factor: 5.157

8.  Expression of autotaxin and lysophosphatidic acid receptors increases mammary tumorigenesis, invasion, and metastases.

Authors:  Shuying Liu; Makiko Umezu-Goto; Mandi Murph; Yiling Lu; Wenbin Liu; Fan Zhang; Shuangxing Yu; L Clifton Stephens; Xiaojiang Cui; George Murrow; Kevin Coombes; William Muller; Mien-Chie Hung; Charles M Perou; Adrian V Lee; Xianjun Fang; Gordon B Mills
Journal:  Cancer Cell       Date:  2009-06-02       Impact factor: 31.743

9.  Structural basis of substrate discrimination and integrin binding by autotaxin.

Authors:  Jens Hausmann; Satwik Kamtekar; Evangelos Christodoulou; Jacqueline E Day; Tao Wu; Zachary Fulkerson; Harald M H G Albers; Laurens A van Meeteren; Anna J S Houben; Leonie van Zeijl; Silvia Jansen; Maria Andries; Troii Hall; Lyle E Pegg; Timothy E Benson; Mobien Kasiem; Karl Harlos; Craig W Vander Kooi; Susan S Smyth; Huib Ovaa; Mathieu Bollen; Andrew J Morris; Wouter H Moolenaar; Anastassis Perrakis
Journal:  Nat Struct Mol Biol       Date:  2011-01-16       Impact factor: 15.369
  9 in total
  11 in total

1.  Binding of autotaxin to integrins localizes lysophosphatidic acid production to platelets and mammalian cells.

Authors:  Zachary Fulkerson; Tao Wu; Manjula Sunkara; Craig Vander Kooi; Andrew J Morris; Susan S Smyth
Journal:  J Biol Chem       Date:  2011-08-10       Impact factor: 5.157

2.  Allergic to autotaxin. A new role for lysophospholipase d and lysophosphatidic Acid in asthma?

Authors:  Steve N Georas
Journal:  Am J Respir Crit Care Med       Date:  2013-10-15       Impact factor: 21.405

3.  Lysophosphatidic acid inhibits CD8 T cell activation and control of tumor progression.

Authors:  Shannon K Oda; Pamela Strauch; Yuko Fujiwara; Amin Al-Shami; Tamas Oravecz; Gabor Tigyi; Roberta Pelanda; Raul M Torres
Journal:  Cancer Immunol Res       Date:  2013-10       Impact factor: 11.151

Review 4.  Autotaxin, a lysophospholipase D with pleomorphic effects in oncogenesis and cancer progression.

Authors:  Lorenzo Federico; Kang Jin Jeong; Christopher P Vellano; Gordon B Mills
Journal:  J Lipid Res       Date:  2015-05-14       Impact factor: 5.922

5.  Selective export of autotaxin from the endoplasmic reticulum.

Authors:  Lin Lyu; Baolu Wang; Chaoyang Xiong; Xiaotian Zhang; Xiaoyan Zhang; Junjie Zhang
Journal:  J Biol Chem       Date:  2017-03-15       Impact factor: 5.157

6.  Lysophosphatidic acid induces lymphangiogenesis and IL-8 production in vitro in human lymphatic endothelial cells.

Authors:  Hong Mu; Tiffany L Calderone; Michael A Davies; Victor G Prieto; Hua Wang; Gordon B Mills; Menashe Bar-Eli; Jeffrey E Gershenwald
Journal:  Am J Pathol       Date:  2012-03-30       Impact factor: 4.307

Review 7.  Bioactive lysophospholipids: role in regulation of aqueous humor outflow and intraocular pressure in the context of pathobiology and therapy of glaucoma.

Authors:  Ponugoti Vasantha Rao
Journal:  J Ocul Pharmacol Ther       Date:  2013-11-27       Impact factor: 2.671

8.  Lysophosphatidic acid receptor 5 inhibits B cell antigen receptor signaling and antibody response.

Authors:  Jiancheng Hu; Shannon K Oda; Kristin Shotts; Erin E Donovan; Pamela Strauch; Lindsey M Pujanauski; Francisco Victorino; Amin Al-Shami; Yuko Fujiwara; Gabor Tigyi; Tamas Oravecz; Roberta Pelanda; Raul M Torres
Journal:  J Immunol       Date:  2014-06-02       Impact factor: 5.422

9.  LPA5 Is an Inhibitory Receptor That Suppresses CD8 T-Cell Cytotoxic Function via Disruption of Early TCR Signaling.

Authors:  Divij Mathew; Kimberly N Kremer; Pamela Strauch; Gabor Tigyi; Roberta Pelanda; Raul M Torres
Journal:  Front Immunol       Date:  2019-05-28       Impact factor: 7.561

Review 10.  Coming of Age for Autotaxin and Lysophosphatidate Signaling: Clinical Applications for Preventing, Detecting and Targeting Tumor-Promoting Inflammation.

Authors:  Matthew G K Benesch; Iain T K MacIntyre; Todd P W McMullen; David N Brindley
Journal:  Cancers (Basel)       Date:  2018-03-15       Impact factor: 6.639
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