BACKGROUND: Children with prenatal alcohol exposure (PAE) and Fetal Alcohol Spectrum Disorders (FASD) display numerous neuropsychological impairments, including deficits on measures of executive functioning (EF) and working memory. OBJECTIVES: The goal of this project was to examine whether children with PAE and FASD demonstrate EF and working memory deficits on the CANTAB® (a computerized neuropsychological test). METHODS: Twenty-four children with PAE and 26 control children were tested on the CANTAB®. RESULTS: Children with PAE demonstrated deficits in the areas of executive functioning, working memory, and attention. Among the PAE group, those with FASD were specifically impaired on working memory capacity. CONCLUSIONS: The CANTAB® is a useful tool for detecting neurobehavioral deficits in children with PAE.
BACKGROUND:Children with prenatal alcohol exposure (PAE) and Fetal Alcohol Spectrum Disorders (FASD) display numerous neuropsychological impairments, including deficits on measures of executive functioning (EF) and working memory. OBJECTIVES: The goal of this project was to examine whether children with PAE and FASD demonstrate EF and working memory deficits on the CANTAB® (a computerized neuropsychological test). METHODS: Twenty-four children with PAE and 26 control children were tested on the CANTAB®. RESULTS:Children with PAE demonstrated deficits in the areas of executive functioning, working memory, and attention. Among the PAE group, those with FASD were specifically impaired on working memory capacity. CONCLUSIONS: The CANTAB® is a useful tool for detecting neurobehavioral deficits in children with PAE.
Authors: Owen W W Nkhoma; Maresa E Duffy; Deborah A Cory-Slechta; Philip W Davidson; Emeir M McSorley; J J Strain; Gerard M O'Brien Journal: J Nutr Date: 2013-06-26 Impact factor: 4.798
Authors: Tanya T Nguyen; Ashkan Ashrafi; Jennifer D Thomas; Edward P Riley; Roger W Simmons Journal: Neurotoxicol Teratol Date: 2012-12-11 Impact factor: 3.763
Authors: M Alejandra Infante; Eileen M Moore; Amanda Bischoff-Grethe; Susan F Tapert; Sarah N Mattson; Edward P Riley Journal: Alcohol Date: 2017-08-12 Impact factor: 2.405