BACKGROUND: The systemic nature of atherosclerosis compromises medium-term survival following major vascular surgery. Neutrophil-lymphocyte ratio (NLR) is a simple index of systemic inflammatory burden which correlates with survival following percutaneous coronary intervention. METHODS: Patients undergoing elective major vascular surgery in 2 tertiary vascular units were identified from prospectively maintained databases. Factors associated with 2-year mortality were assessed by univariate and multivariate analyses. RESULTS: Over a 4-year period, 1021 patients underwent elective major vascular surgery (carotid endarterectomy, abdominal aortic aneurysm repair, lower limb revascularization). Two-year mortality was 11.2%. In multivariate analysis, preoperative NLR > 5 was independently associated with 2-year mortality (multivariate odds ratio [OR] 2.21; 95% confidence interval [CI] 1.22-4.01). CONCLUSION: Preoperative NLR identifies patients at increased risk of death within 2 years of major vascular surgery. This simple index may facilitate targeted preventive measures for high-risk patients.
BACKGROUND: The systemic nature of atherosclerosis compromises medium-term survival following major vascular surgery. Neutrophil-lymphocyte ratio (NLR) is a simple index of systemic inflammatory burden which correlates with survival following percutaneous coronary intervention. METHODS:Patients undergoing elective major vascular surgery in 2 tertiary vascular units were identified from prospectively maintained databases. Factors associated with 2-year mortality were assessed by univariate and multivariate analyses. RESULTS: Over a 4-year period, 1021 patients underwent elective major vascular surgery (carotid endarterectomy, abdominal aortic aneurysm repair, lower limb revascularization). Two-year mortality was 11.2%. In multivariate analysis, preoperative NLR > 5 was independently associated with 2-year mortality (multivariate odds ratio [OR] 2.21; 95% confidence interval [CI] 1.22-4.01). CONCLUSION: Preoperative NLR identifies patients at increased risk of death within 2 years of major vascular surgery. This simple index may facilitate targeted preventive measures for high-risk patients.
Authors: Hakan Taşolar; Mehmet Ballı; Mustafa Çetin; Yılmaz Ömür Otlu; Burak Altun; Adil Bayramoğlu Journal: Ann Noninvasive Electrocardiol Date: 2014-06-16 Impact factor: 1.468
Authors: Katherine M Reitz; Oscar C Marroquin; Mazen S Zenati; Jason Kennedy; Mary Korytkowski; Edith Tzeng; Stephen Koscum; David Newhouse; Ricardo Martinez Garcia; Jennifer Vates; Timothy R Billiar; Brian S Zuckerbraun; Richard L Simmons; Stephen Shapiro; Christopher W Seymour; Derek C Angus; Matthew R Rosengart; Matthew D Neal Journal: JAMA Surg Date: 2020-06-17 Impact factor: 14.766
Authors: S Karakoyun; M O Gürsoy; T Akgün; L Öcal; M Kalçık; M Yesin; E Erdoğan; S Külahçıoğlu; R B Bakal; C Köksal; M Yıldız; M Özkan Journal: Herz Date: 2014-07-26 Impact factor: 1.443
Authors: Fergus Noble; James Hopkins; Nathan Curtis; Jamie J Kelly; Ian S Bailey; James P Byrne; Adrian C Bateman; Andrew R Bateman; Timothy J Underwood Journal: Med Oncol Date: 2013-05-21 Impact factor: 3.064