BACKGROUND: Seizures are important neurologic complications of chronic subdural hematoma (CSDH). A better understanding of risk factors of seizures following CSDH is needed to identify the patient who will require treatment. METHODS: This one-year retrospective study enrolled 100 adult CSDH patients. Baseline prognostic variables were analyzed by Cox's proportional hazards model after a minimum of 18 months of follow-up. RESULTS: Seizures occurred in 11 CSDH patients, including acute symptomatic seizures in 6.0% (6/100) and unprovoked seizures in 5.0% (5/100). None progressed to status epilepticus during hospitalization. After a minimum of 18 months of follow-up, the mean Glasgow Outcome Scores (GOSs) were 4.1 ± 1.4 and 4.7 ± 0.7 for patients with and without seizures, respectively. Cox's proportional hazards model showed that only the mean GCS on admission (P = 0.004, OR = 0.78, 95% CI = 0.67-0.93) was independently associated with seizures, and a decrease of one mean GCS increased the seizure rate by 21.6%. CONCLUSION: Lower mean GCS on admission is independently predictive of seizures, most of which occur within the first three months after CSDH.
BACKGROUND:Seizures are important neurologic complications of chronic subdural hematoma (CSDH). A better understanding of risk factors of seizures following CSDH is needed to identify the patient who will require treatment. METHODS: This one-year retrospective study enrolled 100 adult CSDH patients. Baseline prognostic variables were analyzed by Cox's proportional hazards model after a minimum of 18 months of follow-up. RESULTS:Seizures occurred in 11 CSDH patients, including acute symptomatic seizures in 6.0% (6/100) and unprovoked seizures in 5.0% (5/100). None progressed to status epilepticus during hospitalization. After a minimum of 18 months of follow-up, the mean Glasgow Outcome Scores (GOSs) were 4.1 ± 1.4 and 4.7 ± 0.7 for patients with and without seizures, respectively. Cox's proportional hazards model showed that only the mean GCS on admission (P = 0.004, OR = 0.78, 95% CI = 0.67-0.93) was independently associated with seizures, and a decrease of one mean GCS increased the seizure rate by 21.6%. CONCLUSION: Lower mean GCS on admission is independently predictive of seizures, most of which occur within the first three months after CSDH.
Authors: Joseph Driver; Aislyn C DiRisio; Heidi Mitchell; Zachary D Threlkeld; William B Gormley Journal: Neurocrit Care Date: 2019-02 Impact factor: 3.210
Authors: Hussam Hamou; Mohammed Alzaiyani; Tobias Rossmann; Rastislav Pjontek; Benedikt Kremer; Hasan Zaytoun; Hani Ridwan; Hans Clusmann; Anke Hoellig; Michael Veldeman Journal: Front Neurol Date: 2022-09-08 Impact factor: 4.086
Authors: Ali Seifi; Ali Akbar Asadi-Pooya; Kevin Carr; Mitchell Maltenfort; Mehrdad Emami; Rodney Bell; Michael Moussouttas; Moussa Yazbeck; Fred Rincon Journal: Springerplus Date: 2014-07-01