| Literature DB >> 21286656 |
Anup M Jawalekar1, Marieke Op de Beeck, Floris L van Delft, Annemieke Madder.
Abstract
2'-O-(3-(Furan-2-yl)propyl)adenosine was synthesized and evaluated for interstrand crosslink (ICL) formation in DNA duplexes. In situ oxidation of the furan moiety with NIS showed rapid crosslink formation to dA and dC, while dT and dG were inactive.Entities:
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Year: 2011 PMID： 21286656 DOI： 10.1039/c0cc04667a
Source DB: PubMed Journal: Chem Commun (Camb) ISSN： 1359-7345 Impact factor: 6.222