Literature DB >> 21285230

Biological mechanisms of chronic fatigue.

Katrine B Norheim1, Grete Jonsson, Roald Omdal.   

Abstract

Chronic fatigue is a common, poorly understood and disabling phenomenon in many diseases. We aim to provide an overview of fatigue in chronic autoimmune and inflammatory disease. Fatigue measurement, prevalence and confounding factors such as depression, sleep disorders and pain are reviewed in the first half of the article. In the second half of the article, we describe explanatory models of fatigue and fatigue signalling, with an emphasis on cytokines and sickness behaviour, oxidative stress, mitochondrial dysfunction and the impact of certain genes on fatigue.

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Year:  2011        PMID： 21285230     DOI： 10.1093/rheumatology/keq454

Source DB:  PubMed          Journal:  Rheumatology (Oxford)        ISSN： 1462-0324            Impact factor:   7.580


  59 in total

1.  A possible genetic association with chronic fatigue in primary Sjögren's syndrome: a candidate gene study.

Authors:  Katrine Brække Norheim; Stephanie Le Hellard; Gunnel Nordmark; Erna Harboe; Lasse Gøransson; Johan G Brun; Marie Wahren-Herlenius; Roland Jonsson; Roald Omdal
Journal:  Rheumatol Int       Date:  2013-09-03       Impact factor: 2.631

2.  Measuring fatigue in rheumatoid arthritis.

Authors:  Stephanie Nikolaus; Mart A F J van de Laar
Journal:  Nat Rev Rheumatol       Date:  2011-08-30       Impact factor: 20.543

3.  Raised Serum IL-8 Levels Are Associated with Excessive Fatigue in Female Carriers of X-Linked Chronic Granulomatous Disease in the UK.

Authors:  Alexandra C Battersby; Alexander J Martin; Jessica Tarn; Fai W Ng; Catherine M Cale; David Goldblatt; Andrew R Gennery
Journal:  J Clin Immunol       Date:  2017-03-23       Impact factor: 8.317

4.  Shortened Sleep Duration Causes Sleepiness, Inattention, and Oppositionality in Adolescents With Attention-Deficit/Hyperactivity Disorder: Findings From a Crossover Sleep Restriction/Extension Study.

Authors:  Stephen P Becker; Jeffery N Epstein; Leanne Tamm; Alina A Tilford; Clair M Tischner; Paul A Isaacson; John O Simon; Dean W Beebe
Journal:  J Am Acad Child Adolesc Psychiatry       Date:  2018-11-02       Impact factor: 8.829

5.  Peripheral inflammatory disease associated with centrally activated IL-1 system in humans and mice.

Authors:  Jon Lampa; Marie Westman; Diana Kadetoff; Anna Nordenstedt Agréus; Erwan Le Maître; Caroline Gillis-Haegerstrand; Magnus Andersson; Mohsen Khademi; Maripat Corr; Christina A Christianson; Ada Delaney; Tony L Yaksh; Eva Kosek; Camilla I Svensson
Journal:  Proc Natl Acad Sci U S A       Date:  2012-07-16       Impact factor: 11.205

6.  Do sleep complaints predict persistent fatigue in older adults?

Authors:  Yohannes W Endeshaw
Journal:  J Am Geriatr Soc       Date:  2015-04-06       Impact factor: 5.562

7.  Differing leukocyte gene expression profiles associated with fatigue in patients with prostate cancer versus chronic fatigue syndrome.

Authors:  Kathleen C Light; Neeraj Agarwal; Eli Iacob; Andrea T White; Anita Y Kinney; Timothy A VanHaitsma; Hannah Aizad; Ronald W Hughen; Lucinda Bateman; Alan R Light
Journal:  Psychoneuroendocrinology       Date:  2013-09-06       Impact factor: 4.905

Review 8.  Fatigue in rheumatic diseases.

Authors:  Sevinç Can Sandıkçı; Zeynep Özbalkan
Journal:  Eur J Rheumatol       Date:  2015-09-01

Review 9.  Reflections on 'older' drugs: learning new lessons in rheumatology.

Authors:  S A Kerrigan; I B McInnes
Journal:  Nat Rev Rheumatol       Date:  2020-02-17       Impact factor: 20.543

10.  Chronic pain. Decreased motivation during chronic pain requires long-term depression in the nucleus accumbens.

Authors:  Neil Schwartz; Paul Temkin; Sandra Jurado; Byung Kook Lim; Boris D Heifets; Jai S Polepalli; Robert C Malenka
Journal:  Science       Date:  2014-08-01       Impact factor: 47.728
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