Nowell Solish1, Arthur Swift. 1. The University of Toronto, Toronto, Ontario, Canada. n.solish@utoronto.ca
Abstract
BACKGROUND: There have been few systematic investigations of the effectiveness, safety and tolerability of aesthetic lip augmentation using hyaluronic acid (HA) fillers. OBJECTIVES: Evaluate the effectiveness of small gel particle hyaluronic acid filler (Restylane Injectable Gel [SGP-HA]; Medicis Aesthetics Inc., Scottsdale, AZ) in lip augmentation using the Medicis Lip Fullness Scale (MLFS). Assess subjective improvement in lip appearance using the Global Aesthetic Improvement Scale (GAIS). PATIENTS, MATERIALS AND METHODS: Investigators treated 21 adults. The primary efficacy endpoint was an increase in lip fullness at least one grade on MLFS at eight weeks post-treatment. Adverse events were reported using patient diaries. RESULTS: Sixteen of 18 evaluable subjects (89%) had an improvement at least one grade on MLFS in both lips. MLFS and GAIS scores were consistent, suggesting clinically significant aesthetic improvement. Adverse effects were transient and mostly mild to moderate in severity. CONCLUSION: Lip augmentation with SGP-HA was well tolerated and resulted in clinically meaningful increases in lip fullness.
BACKGROUND: There have been few systematic investigations of the effectiveness, safety and tolerability of aesthetic lip augmentation using hyaluronic acid (HA) fillers. OBJECTIVES: Evaluate the effectiveness of small gel particle hyaluronic acid filler (Restylane Injectable Gel [SGP-HA]; Medicis Aesthetics Inc., Scottsdale, AZ) in lip augmentation using the Medicis Lip Fullness Scale (MLFS). Assess subjective improvement in lip appearance using the Global Aesthetic Improvement Scale (GAIS). PATIENTS, MATERIALS AND METHODS: Investigators treated 21 adults. The primary efficacy endpoint was an increase in lip fullness at least one grade on MLFS at eight weeks post-treatment. Adverse events were reported using patient diaries. RESULTS: Sixteen of 18 evaluable subjects (89%) had an improvement at least one grade on MLFS in both lips. MLFS and GAIS scores were consistent, suggesting clinically significant aesthetic improvement. Adverse effects were transient and mostly mild to moderate in severity. CONCLUSION:Lip augmentation with SGP-HA was well tolerated and resulted in clinically meaningful increases in lip fullness.
Authors: Robert Weiss; Kenneth Beer; Sue E Cox; Melanie Palm; Joely Kaufman-Janette; Benjamin Bassichis; Brian Biesman; John Joseph; Birgitta Almegård; Anna Nilsson; Carolina Edwartz Journal: Dermatol Surg Date: 2021-04-01 Impact factor: 2.914
Authors: Nestor Demosthenous; David Eccleston; Vitor Figueiredo; Luis Uva; Graeme Kerson; Michael Silberberg Journal: Aesthet Surg J Open Forum Date: 2022-05-15