| Literature DB >> 21282055 |
Lalgudi S Harikrishnan1, Muthoni G Kamau, Honghe Wan, Jennifer A Inghrim, Kurt Zimmermann, Xiaopeng Sang, Harold A Mastalerz, Walter L Johnson, Guifen Zhang, Louis J Lombardo, Michael A Poss, George L Trainor, John S Tokarski, Matthew V Lorenzi, Dan You, Marco M Gottardis, Kathy F Baldwin, Jonathan Lippy, David S Nirschl, Ruhui Qiu, Arthur V Miller, Javed Khan, John S Sack, Ashok V Purandare.
Abstract
SAR studies of pyrrolo[1,2-f]triazines as JAK2 inhibitors is presented. Achieving JAK2 inhibition selectively over JAK3 is discussed.Entities:
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Year: 2011 PMID： 21282055 DOI： 10.1016/j.bmcl.2011.01.022
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823