Literature DB >> 2128125

Dopamine release and metabolism in the rat striatum: an analysis by 'in vivo' brain microdialysis.

G W Arbuthnott1, I S Fairbrother, S P Butcher.   

Abstract

Brain microdialysis studies on the mechanisms underlying dopamine release in the rat striatum provide evidence that both exocytotic and carrier-dependent processes operate in vivo. While several releasers (potassium, veratrine, amphetamine, ouabain) utilize newly synthesized stores of dopamine, tyramine is uniquely sensitive to depletion of vesicular storage by reserpine. Extracellular DOPAC is closely associated with the newly synthesized pool of dopamine and experiments with selective monoamine oxidase inhibitors suggest that DOPAC is formed mainly by MAO-A. Recent work on the two dopamine receptors suggest that release by different mechanisms may selectively activate D1 or D2 receptor subtypes.

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Year:  1990        PMID: 2128125     DOI: 10.1016/0163-7258(90)90050-c

Source DB:  PubMed          Journal:  Pharmacol Ther        ISSN: 0163-7258            Impact factor:   12.310


  16 in total

1.  Dopaminergic innervation of the rat globus pallidus characterized by microdialysis and immunohistochemistry.

Authors:  Holger Fuchs; Wolfgang Hauber
Journal:  Exp Brain Res       Date:  2003-09-24       Impact factor: 1.972

2.  Progressive dopaminergic alterations and mitochondrial abnormalities in LRRK2 G2019S knock-in mice.

Authors:  M Yue; K M Hinkle; P Davies; E Trushina; F C Fiesel; T A Christenson; A S Schroeder; L Zhang; E Bowles; B Behrouz; S J Lincoln; J E Beevers; A J Milnerwood; A Kurti; P J McLean; J D Fryer; W Springer; D W Dickson; M J Farrer; H L Melrose
Journal:  Neurobiol Dis       Date:  2015-03-31       Impact factor: 5.996

3.  L-DOPA modulation of corpus striatal dopamine and dihydroxyphenylacetic acid output from intact and 6-OHDA lesioned rats.

Authors:  K Xu; D E Dluzen
Journal:  J Neural Transm (Vienna)       Date:  1996       Impact factor: 3.575

4.  Effect of low-dose treatment with selegiline on dopamine transporter (DAT) expression and amphetamine-induced dopamine release in vivo.

Authors:  I Lamensdorf; S Porat; R Simantov; J P Finberg
Journal:  Br J Pharmacol       Date:  1999-02       Impact factor: 8.739

5.  Single prolonged stress decreases sign-tracking and cue-induced reinstatement of cocaine-seeking.

Authors:  Christopher J Fitzpatrick; Lakshmikripa Jagannathan; Elijah D Lowenstein; Terry E Robinson; Jill B Becker; Jonathan D Morrow
Journal:  Behav Brain Res       Date:  2018-08-02       Impact factor: 3.332

6.  Hypothalamic digoxin and schizophrenia - a model for conscious and subliminal perception and its dysfunction in schizophrenia.

Authors:  R A Kurup; J Augustine; P A Kurup
Journal:  Indian J Psychiatry       Date:  1999-07       Impact factor: 1.759

7.  Okadaic acid modulates exocytotic and transporter-dependent release of dopamine in bovine retina in vitro.

Authors:  O Bugnon; S Ofori; M Schorderet
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1995-01       Impact factor: 3.000

8.  Mechanisms underlying domoic acid-induced dopamine release from striatum: an in vivo microdialysis study.

Authors:  M Alfonso; R Durán; F Campos; D Perez-Vences; L R F Faro; B Arias
Journal:  Neurochem Res       Date:  2003-10       Impact factor: 3.996

9.  Correlation between ventral striatal catecholamine content and nociceptive thresholds in neuropathic mice.

Authors:  Anna M W Taylor; Niall P Murphy; Christopher J Evans; Catherine M Cahill
Journal:  J Pain       Date:  2014-06-02       Impact factor: 5.820

10.  Halothane anesthesia affects NMDA-stimulated cholinergic and GABAergic modulation of striatal dopamine efflux and metabolism in the rat in vivo.

Authors:  K J Whitehead; S Rose; P Jenner
Journal:  Neurochem Res       Date:  2004-04       Impact factor: 3.996

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