Literature DB >> 21280069

New pathway links γ-secretase to inflammation and memory while sparing notch.

Sam Gandy, Brandon Wustman.   

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Year:  2011        PMID： 21280069      PMCID： PMC3274708          DOI： 10.1002/ana.22310

Source DB:  PubMed          Journal:  Ann Neurol        ISSN： 0364-5134            Impact factor:   10.422


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  22 in total

1.  A subset of NSAIDs lower amyloidogenic Abeta42 independently of cyclooxygenase activity.

Authors:  S Weggen; J L Eriksen; P Das; S A Sagi; R Wang; C U Pietrzik; K A Findlay; T E Smith; M P Murphy; T Bulter; D E Kang; N Marquez-Sterling; T E Golde; E H Koo
Journal:  Nature       Date:  2001-11-08       Impact factor: 49.962

2.  5-lipoxygenase as an endogenous modulator of amyloid β formation in vivo.

Authors:  Jin Chu; Domenico Praticò
Journal:  Ann Neurol       Date:  2010-11-17       Impact factor: 10.422

Review 3.  Cellular processing of beta-amyloid precursor protein and the genesis of amyloid beta-peptide.

Authors:  C Haass; D J Selkoe
Journal:  Cell       Date:  1993-12-17       Impact factor: 41.582

Review 4.  Novel therapeutic opportunities for Alzheimer's disease: focus on nonsteroidal anti-inflammatory drugs.

Authors:  Kirk P Townsend; Domenico Praticò
Journal:  FASEB J       Date:  2005-10       Impact factor: 5.191

5.  Endoproteolysis of presenilin 1 and accumulation of processed derivatives in vivo.

Authors:  G Thinakaran; D R Borchelt; M K Lee; H H Slunt; L Spitzer; G Kim; T Ratovitsky; F Davenport; C Nordstedt; M Seeger; J Hardy; A I Levey; S E Gandy; N A Jenkins; N G Copeland; D L Price; S S Sisodia
Journal:  Neuron       Date:  1996-07       Impact factor: 17.173

Review 6.  Loss-of-function presenilin mutations in Alzheimer disease. Talking Point on the role of presenilin mutations in Alzheimer disease.

Authors:  Bart De Strooper
Journal:  EMBO Rep       Date:  2007-02       Impact factor: 8.807

7.  Activation of a 15-lipoxygenase/leukotriene pathway in human polymorphonuclear leukocytes by the anti-inflammatory agent ibuprofen.

Authors:  J Y Vanderhoek; J M Bailey
Journal:  J Biol Chem       Date:  1984-06-10       Impact factor: 5.157

8.  Epidermal growth factor receptor and notch pathways participate in the tumor suppressor function of gamma-secretase.

Authors:  Tong Li; Hongjin Wen; Cory Brayton; Pritam Das; Lisa A Smithson; Abdul Fauq; Xing Fan; Barbara J Crain; Donald L Price; Todd E Golde; Charles G Eberhart; Philip C Wong
Journal:  J Biol Chem       Date:  2007-09-07       Impact factor: 5.157

9.  No advantage of A beta 42-lowering NSAIDs for prevention of Alzheimer dementia in six pooled cohort studies.

Authors:  C A Szekely; R C Green; J C S Breitner; T Østbye; A S Beiser; M M Corrada; H H Dodge; M Ganguli; C H Kawas; L H Kuller; B M Psaty; S M Resnick; P A Wolf; A B Zonderman; K A Welsh-Bohmer; P P Zandi
Journal:  Neurology       Date:  2008-05-28       Impact factor: 9.910

10.  Familial Alzheimer's disease in kindreds with missense mutations in a gene on chromosome 1 related to the Alzheimer's disease type 3 gene.

Authors:  E I Rogaev; R Sherrington; E A Rogaeva; G Levesque; M Ikeda; Y Liang; H Chi; C Lin; K Holman; T Tsuda
Journal:  Nature       Date:  1995-08-31       Impact factor: 49.962
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  1 in total

1.  The BET-Bromodomain Inhibitor JQ1 Reduces Inflammation and Tau Phosphorylation at Ser396 in the Brain of the 3xTg Model of Alzheimer's Disease.

Authors:  Marco Magistri; Dmitry Velmeshev; Madina Makhmutova; Prutha Patel; Gregory C Sartor; Claude-Henry Volmar; Claes Wahlestedt; Mohammad Ali Faghihi
Journal:  Curr Alzheimer Res       Date:  2016       Impact factor: 3.498
  1 in total

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