Literature DB >> 21279881

Triterpenoid saponins from Gynostemma pentaphyllum.

Lin Shi1, Jia-Qing Cao, Sheng-Ming Shi, Yu-Qing Zhao.   

Abstract

Four new dammarane-type triterpene saponins, 1-4, were isolated from the aerial parts of Gynostemma pentaphyllum (Thunb.) Makino. Their structural elucidations were accomplished mainly on the basis of spectroscopic methods, such as IR, HR-TOF-MS, and NMR. Compounds 1-4 showed moderate cytotoxic activities against cancer cell lines HL-60, Colon205, and Du145 in vitro.

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Year:  2011        PMID： 21279881     DOI： 10.1080/10286020.2010.547029

Source DB:  PubMed          Journal:  J Asian Nat Prod Res        ISSN： 1028-6020            Impact factor:   1.569


  5 in total

Review 1.  Anti-cancer effects of Gynostemma pentaphyllum (Thunb.) Makino (Jiaogulan).

Authors:  Yantao Li; Wanjun Lin; Jiajun Huang; Ying Xie; Wenzhe Ma
Journal:  Chin Med       Date:  2016-09-27       Impact factor: 5.455

2.  Transcriptome Sequencing of Gynostemma pentaphyllum to Identify Genes and Enzymes Involved in Triterpenoid Biosynthesis.

Authors:  Qicong Chen; Chengtong Ma; Jieying Qian; Xiuwan Lan; Naixia Chao; Jian Sun; Yaosheng Wu
Journal:  Int J Genomics       Date:  2016-12-14       Impact factor: 2.326

3.  Profiling and activity screening of Dammarane-type triterpen saponins from Gynostemma pentaphyllum with glucose-dependent insulin secretory activity.

Authors:  Lena C E Lundqvist; Darren Rattigan; Emad Ehtesham; Camila Demmou; Claes-Göran Östenson; Corine Sandström
Journal:  Sci Rep       Date:  2019-01-24       Impact factor: 4.379

4.  In Vitro Anticancer Activity of a Nonpolar Fraction from Gynostemma pentaphyllum (Thunb.) Makino.

Authors:  Yantao Li; Jiajun Huang; Wanjun Lin; Zhongwen Yuan; Senling Feng; Ying Xie; Wenzhe Ma
Journal:  Evid Based Complement Alternat Med       Date:  2016-02-29       Impact factor: 2.629

5.  Gene excavation and expression analysis of CYP and UGT related to the post modifying stage of gypenoside biosynthesis in Gynostemma pentaphyllum (Thunb.) Makino by comprehensive analysis of RNA and proteome sequencing.

Authors:  Yangmei Zhang; Qicong Chen; Yuanheng Huang; Ruiqiang Zhao; Jian Sun; Xidong Yuan; Huiming Xu; Huiyu Liu; Yaosheng Wu
Journal:  PLoS One       Date:  2021-12-07       Impact factor: 3.240
  5 in total

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