Literature DB >> 2127913

Is there a rational basis for the different spectra of adverse effects of nonsteroidal anti-inflammatory drugs (NSAIDs)?

K Brune1.   

Abstract

NSAIDs, particularly those related to aspirin, are all known to cause adverse effects, notably in the gastrointestinal tract, blood, liver and kidney, in addition to allergic and pseudo-allergic reactions. In the past decade, there have been many attempts to elucidate the cause(s) of these adverse effects so that new NSAIDs which are widely devoid of them can be developed. As a result, a number of concepts have been formulated which may well have considerable influence upon the future development of NSAIDs.

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Year:  1990        PMID： 2127913     DOI： 10.2165/00003495-199000405-00004

Source DB:  PubMed          Journal:  Drugs        ISSN： 0012-6667            Impact factor:   9.546


  15 in total

1.  Acidic antiinflammatory agents--correlations of some physical, pharmacological and clinical data.

Authors:  J G Lombardino; I G Otterness; E H Wiseman
Journal:  Arzneimittelforschung       Date:  1975-10

2.  Parietal cells of the stomach trap salicylates during absorption.

Authors:  K Brune; A Schweitzer; H Eckert
Journal:  Biochem Pharmacol       Date:  1977-09-15       Impact factor: 5.858

3.  Non-steroidal anti-inflammatory drugs and serious gastrointestinal adverse reactions--2.

Authors: 
Journal:  Br Med J (Clin Res Ed)       Date:  1986-05-03

4.  FDA Arthritis Advisory Committee meeting: postmarketing surveillance of nonsteroidal antiinflammatory drugs.

Authors:  H E Paulus
Journal:  Arthritis Rheum       Date:  1985-10

5.  Autoradiographic and biochemical observations on the distribution of non-steroid anti-inflammatory drugs.

Authors:  K D Rainsford; A Schweitzer; K Brune
Journal:  Arch Int Pharmacodyn Ther       Date:  1981-04

Review 6.  Recent insight into the mechanism of gastrointestinal tract ulceration.

Authors:  K Brune; K Dietzel; B Nürnberg; H T Schneider
Journal:  Scand J Rheumatol Suppl       Date:  1987

7.  Non-steroidal anti-inflammatory drugs and bleeding peptic ulcer.

Authors:  K Somerville; G Faulkner; M Langman
Journal:  Lancet       Date:  1986-03-01       Impact factor: 79.321

8.  Pharmacological control of leukotriene and prostaglandin production from mouse peritoneal macrophages.

Authors:  K Brune; U Aehringhaus; B A Peskar
Journal:  Agents Actions       Date:  1984-06

Review 9.  Aspirin and allergic diseases: a review.

Authors:  G A Settipane
Journal:  Am J Med       Date:  1983-06-14       Impact factor: 4.965

10.  A comparative endoscopic evaluation of the damaging effects of nonsteroidal anti-inflammatory agents on the gastric and duodenal mucosa.

Authors:  F L Lanza; G L Royer; R S Nelson; T T Chen; C E Seckman; M F Rack
Journal:  Am J Gastroenterol       Date:  1981-01       Impact factor: 10.864
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  3 in total

Review 1.  Preclinical and clinical development of dexketoprofen.

Authors:  D Mauleón; R Artigas; M L García; G Carganico
Journal:  Drugs       Date:  1996       Impact factor: 9.546

Review 2.  Determining small bowel integrity following drug treatment.

Authors:  Simon Smale; Ingvar Bjarnason
Journal:  Br J Clin Pharmacol       Date:  2003-09       Impact factor: 4.335

3.  Renal effects of nimesulide in furosemide-treated subjects.

Authors:  F Steinhäuslin; A Munafo; T Buclin; A Macciocchi; J Biollaz
Journal:  Drugs       Date:  1993       Impact factor: 9.546
  3 in total

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