Literature DB >> 21278778

Raging hormones: gender and renal disease.

Sharon R Silbiger1.   

Abstract

Gender affects the progression of renal disease. In a variety of animal models and in certain human renal diseases, females exhibit a more modest course of kidney disease. Estrogens and testosterone have been implicated in this gender disparity. Doublier and colleagues explore the direct effects of sex hormones on podocyte viability in the α-estrogen receptor knockout (αERKO) mouse. They report that testosterone induces, and estradiol inhibits, podocyte damage in this model.

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Year:  2011        PMID： 21278778     DOI： 10.1038/ki.2010.474

Source DB:  PubMed          Journal:  Kidney Int        ISSN： 0085-2538            Impact factor:   10.612


  13 in total

1.  Sex-Related Disparities in CKD Progression.

Authors:  Ana C Ricardo; Wei Yang; Daohang Sha; Lawrence J Appel; Jing Chen; Marie Krousel-Wood; Anjella Manoharan; Susan Steigerwalt; Jackson Wright; Mahboob Rahman; Sylvia E Rosas; Milda Saunders; Kumar Sharma; Martha L Daviglus; James P Lash
Journal:  J Am Soc Nephrol       Date:  2018-12-03       Impact factor: 10.121

Review 2.  Sex differences in transplantation.

Authors:  Jeremiah D Momper; Michael L Misel; Dianne B McKay
Journal:  Transplant Rev (Orlando)       Date:  2017-02-20       Impact factor: 3.943

3.  Sex Differences in Renal Inflammation and Injury in High-Fat Diet-Fed Dahl Salt-Sensitive Rats.

Authors:  Roxanne Fernandes; Hannah Garver; Jack R Harkema; James J Galligan; Gregory D Fink; Hui Xu
Journal:  Hypertension       Date:  2018-11       Impact factor: 10.190

4.  Androgen-STAT3 activation may contribute to gender disparity in human simply renal cysts.

Authors:  Min Liu; Yun-Fei Xu; Yuan Feng; Wei Zhai; Jian-Ping Che; Sheng-Qiang Xia; Guang-Chun Wang; Jun-Hua Zheng
Journal:  Int J Clin Exp Pathol       Date:  2013-03-15

5.  The SSLepR mutant rat represents a novel model to study obesity-induced renal injury before puberty.

Authors:  Bibek Poudel; Corbin A Shields; Ubong S Ekperikpe; Andrea K Brown; Olivia K Travis; Jordan C Maury; Sarah Fitzgerald; Stanley V Smith; Denise C Cornelius; Jan M Williams
Journal:  Am J Physiol Regul Integr Comp Physiol       Date:  2022-02-02       Impact factor: 3.619

6.  Increased cardiovascular and renal risk is associated with low nephron endowment in aged females: an ovine model of fetal unilateral nephrectomy.

Authors:  Reetu R Singh; Andrew J Jefferies; Yugeesh R Lankadeva; Paul Lombardo; Michal Schneider-Kolsky; Lucinda Hilliard; Kate M Denton; Karen M Moritz
Journal:  PLoS One       Date:  2012-08-03       Impact factor: 3.240

7.  Estrogen preserves split renal function in a chronic complete unilateral ureteral obstruction animal model.

Authors:  Shanhua Mao; Hua Xu; Lujia Zou; Gang Xu; Zhong Wu; Qiang Ding; Haowen Jiang
Journal:  Exp Ther Med       Date:  2014-04-03       Impact factor: 2.447

8.  Is Testosterone Detrimental to Renal Function?

Authors:  Guido Filler; Amanda Ramsaroop; Robert Stein; Claire Grant; Raanan Marants; Aaron So; Christopher McIntyre
Journal:  Kidney Int Rep       Date:  2016-07-21

9.  Serum uromodulin-a marker of kidney function and renal parenchymal integrity.

Authors:  Jürgen E Scherberich; Rudolf Gruber; Wolfgang Andreas Nockher; Erik Ilsø Christensen; Hans Schmitt; Victor Herbst; Matthias Block; Jürgen Kaden; Wolfgang Schlumberger
Journal:  Nephrol Dial Transplant       Date:  2018-02-01       Impact factor: 5.992

Review 10.  Sex and the kidneys: current understanding and research opportunities.

Authors:  C Noel Bairey Merz; Laura M Dember; Julie R Ingelfinger; Amanda Vinson; Joel Neugarten; Kathryn L Sandberg; Jennifer C Sullivan; Christine Maric-Bilkan; Tracy L Rankin; Paul L Kimmel; Robert A Star
Journal:  Nat Rev Nephrol       Date:  2019-10-04       Impact factor: 28.314
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