Literature DB >> 2127795

A sensitive method for determination of cholesterol growth using model solutions of supersaturated bile.

N Busch1, H Tokumo, R T Holzbach.   

Abstract

We describe a novel, facile, and highly reproducible spectrophotometric technique to measure a cholesterol crystal growth curve. This method permits a quantitative estimate of the potency or comparative abundance of a given kinetic effector substance. In addition to several internal validation procedures, data are provided that support the usefulness of the technique in the assay of substances with either known promoting activity, i.e., human mucin glycoprotein, or those with known inhibitory activity, i.e., human apolipoprotein A-I.

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Year:  1990        PMID: 2127795

Source DB:  PubMed          Journal:  J Lipid Res        ISSN: 0022-2275            Impact factor:   5.922


  13 in total

Review 1.  Cholesterol crystallisation in bile.

Authors:  P Portincasa; K J van Erpecum; G P Vanberge-Henegouwen
Journal:  Gut       Date:  1997-08       Impact factor: 23.059

2.  Less hydrophobic phosphatidylcholine species simplify biliary vesicle morphology, but induce bile metastability with a broad spectrum of crystal forms.

Authors:  Minoru Sakomoto; Susumu Tazuma; Kazuaki Chayama
Journal:  Biochem J       Date:  2002-02-15       Impact factor: 3.857

3.  Quantitative assessment of comparative potencies of cholesterol-crystal-promoting factors: relation to mechanistic characterization.

Authors:  T Nishioka; S Tazuma; G Yamashita; G Kajiyama
Journal:  Biochem J       Date:  1998-06-01       Impact factor: 3.857

4.  Lecithin hydrophobicity modulates the process of cholesterol crystal nucleation and growth in supersaturated model bile systems.

Authors:  H Ochi; S Tazuma; G Kajiyama
Journal:  Biochem J       Date:  1996-08-15       Impact factor: 3.857

5.  Partial replacement of bile salts causes marked changes of cholesterol crystallization in supersaturated model bile systems.

Authors:  T Nishioka; S Tazuma; G Yamashita; G Kajiyama
Journal:  Biochem J       Date:  1999-06-01       Impact factor: 3.857

6.  Cholesterol crystal binding of biliary immunoglobulin A: visualization by fluorescence light microscopy.

Authors:  F Lammert; S Südfeld; N Busch; S Matern
Journal:  World J Gastroenterol       Date:  2001-04       Impact factor: 5.742

7.  A new subgroup of lectin-bound biliary proteins binds to cholesterol crystals, modifies crystal morphology, and inhibits cholesterol crystallization.

Authors:  N Busch; F Lammert; H U Marschall; S Matern
Journal:  J Clin Invest       Date:  1995-12       Impact factor: 14.808

8.  Human gallstones contain pronucleating nonmucin glycoproteins that are immunoglobulins.

Authors:  P A Lipsett; J Hildreth; H S Kaufman; K D Lillemoe; H A Pitt
Journal:  Ann Surg       Date:  1994-01       Impact factor: 12.969

9.  Biliary alpha 1-acid glycoprotein concentrations in gallstone-free controls and in patients with multiple or solitary cholesterol gallstones.

Authors:  H Nuutinen; M Abei; J Schwarzendrube; S Ginanni Corradini; R M Walsh; P Kawczak; R T Holzbach
Journal:  Dig Dis Sci       Date:  1995-08       Impact factor: 3.199

10.  Comparative effects on biliary concanavalin A-bound glycoproteins and calcium ion on cholesterol crystal nucleation and growth in model bile.

Authors:  K Teramen; S Tazuma; T Ohya; G Kajiyama
Journal:  J Gastroenterol       Date:  1995-08       Impact factor: 7.527

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