| Literature DB >> 21277360 |
Li Li1, Xueyang Deng, Lixia Zhang, Pan Shu, Minjian Qin.
Abstract
A new coumestan, 1,3,9-trihydroxy-8-methoxycoumestan, named flemicoumestan A 1 together with nine isoflavone-related compounds were isolated from the ethyl acetate extract of the roots of Flemingia philippinensis. Their structures were elucidated and confirmed by spectroscopic methods and literature data. Compounds 3 and 4 showed strong lymphocyte proliferation inhibitory activity with an IC(50) value of 1.04-2.76 μM, and the low cytotoxicity with the CC(50) value of 71.01 and 56.36 μM, respectively.Entities:
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Year: 2011 PMID： 21277360 DOI： 10.1016/j.fitote.2011.01.019
Source DB: PubMed Journal: Fitoterapia ISSN： 0367-326X Impact factor: 2.882