| Literature DB >> 21276934 |
Martina Semenzato1, Sara Cogliati, Luca Scorrano.
Abstract
Proapoptotic drugs targeting the mitochondrial Bcl-2 rheostat of apoptosis are tools to selectively kill cancer cells. Sato et al. (2011) expand the available toolkit by identifying the target of the cytotoxic natural product aurilide in the prohibitin Opa1-dependent apoptotic cristae remodeling.Entities:
Year: 2011 PMID: 21276934 DOI: 10.1016/j.chembiol.2011.01.001
Source DB: PubMed Journal: Chem Biol ISSN: 1074-5521