Literature DB >> 21276385

Paraneoplastic Addisonian pigmentation and acquired ichthyosis as presenting features of multiple myeloma.

Nasser Rashid Dar1, Naeem Raza, Azmat Khan, Muhammad Umar Amin.   

Abstract

Black brown hyperpigmentation of the mucosae, sunexposed skin, palmar creases and frictional sites (Addisonian pigmentation) is characteristic of Addison disease. However, it can also occur as a paraneoplastic manifestation of tumours like bronchogenic carcinoma. Acquired ichthyosis starts later in life and can also be a paraneoplastic presentation. We report a unique combination of paraneoplastic Addisonian pigmentation and acquired ichthyosis as presenting features in a patient with undiagnosed multiple myeloma. To the best of our knowledge this combination of paraneoplastic dermatosis has not been documented before in multiple myeloma. It is concluded that the presence of more than one suspicious dermatosis may be an indicator of being paraneoplastic requiring necessary work-up.

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Year:  2011        PMID: 21276385     DOI: 01.2011/JCPSP.4042

Source DB:  PubMed          Journal:  J Coll Physicians Surg Pak        ISSN: 1022-386X            Impact factor:   0.711


  1 in total

1.  Multiple paraneoplastic syndromes revealing non-small cell lung carcinoma.

Authors:  Monia Youssef; Melek Kechida; Saoussen Cheikhmohamed; Adnene Moussa
Journal:  Pan Afr Med J       Date:  2014-11-03
  1 in total

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