Literature DB >> 21276310

Low agreement between the T-SPOT®.TB assay and the tuberculin skin test among college students in China.

J Zhao1, Y Wang, H Wang, C Jiang, Z Liu, X Meng, G Song, N Cheng, E A Graviss, X Ma.   

Abstract

T-SPOT®.TB and the tuberculin skin test (TST) were used to screen for latent tuberculosis infection among 899 Chinese college students. The positivity rates for T-SPOT®.TB and TST were respectively 13.0% (95% confidence interval [CI] 10.4-15.9) and 24.9% (95%CI 21.5-28.6) among students with a bacille Calmette-Guérin (BCG) scar (agreement of both tests 72.3%; 95%CI 68.6-75.8; κ = 0.118), and respectively 17.3% (95%CI 11.7-24.2) and 23.7% (95%CI 17.3-31.2) among those without a BCG scar (agreement 73.1%; 95%CI 65.4-79.9; κ = 0.179). These results demonstrate low agreement between the TST and T-SPOT.TB in the Chinese population studied.

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Year:  2011        PMID: 21276310      PMCID: PMC3118013     

Source DB:  PubMed          Journal:  Int J Tuberc Lung Dis        ISSN: 1027-3719            Impact factor:   2.373


  6 in total

Review 1.  False-positive tuberculin skin tests: what is the absolute effect of BCG and non-tuberculous mycobacteria?

Authors:  M Farhat; C Greenaway; M Pai; D Menzies
Journal:  Int J Tuberc Lung Dis       Date:  2006-11       Impact factor: 2.373

2.  Evaluation of an interferon-gamma release assay, T-SPOT.TB, in a population with a low prevalence of tuberculosis.

Authors:  D R Bienek; C K Chang
Journal:  Int J Tuberc Lung Dis       Date:  2009-11       Impact factor: 2.373

3.  Tuberculin skin testing compared with T-cell responses to Mycobacterium tuberculosis-specific and nonspecific antigens for detection of latent infection in persons with recent tuberculosis contact.

Authors:  S M Arend; A C Engelhard; G Groot; K de Boer; P Andersen; T H Ottenhoff; J T van Dissel
Journal:  Clin Diagn Lab Immunol       Date:  2001-11

4.  BCG in China.

Authors:  Z R Chen; X H Wei; Z Y Zhu
Journal:  Chin Med J (Engl)       Date:  1982-06       Impact factor: 2.628

5.  A meta-analysis of the effect of Bacille Calmette Guérin vaccination on tuberculin skin test measurements.

Authors:  L Wang; M O Turner; R K Elwood; M Schulzer; J M FitzGerald
Journal:  Thorax       Date:  2002-09       Impact factor: 9.139

Review 6.  Systematic review: T-cell-based assays for the diagnosis of latent tuberculosis infection: an update.

Authors:  Madhukar Pai; Alice Zwerling; Dick Menzies
Journal:  Ann Intern Med       Date:  2008-06-30       Impact factor: 25.391

  6 in total
  2 in total

1.  The performance and limitation of T-SPOT.TB for the diagnosis of TB in a high prevalence setting.

Authors:  Changtai Zhu; Zhonghua Liu; Zhiqiang Li; Shencong Mei; Zhongyi Hu
Journal:  J Thorac Dis       Date:  2014-06       Impact factor: 2.895

2.  Interferon-gamma release assay for the diagnosis of latent tuberculosis infection: A latent-class analysis.

Authors:  Tan N Doan; Damon P Eisen; Morgan T Rose; Andrew Slack; Grace Stearnes; Emma S McBryde
Journal:  PLoS One       Date:  2017-11-28       Impact factor: 3.240

  2 in total

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