Literature DB >> 2127350

Cloning and characterization of a DNA fragment that confers sulfonamide resistance in a serogroup B, serotype 15 strain of Neisseria meningitidis.

B E Kristiansen1, P Rådström, A Jenkins, E Ask, B Facinelli, O Sköld.   

Abstract

By cloning studies and complementation experiments, the sulfonamide resistance gene of a serogroup B and serotype 15 (B:15) strain of Neisseria meningitidis was localized to a 1.2-kb chromosomal SspI fragment expressing a drug-resistant dihydropteroate synthase. The fragment hybridized to DNA from both resistant and susceptible strains, suggesting that the resistance gene is a variant of the normal gene for dihydropteroate synthase.

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Year:  1990        PMID： 2127350      PMCID： PMC172039          DOI： 10.1128/AAC.34.11.2277

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  12 in total

1.  Antibiotic prophylaxis of carriers of sulfadiazine-resistant meningococci.

Authors:  J M Dowd; D Blink; C H Miller; P F Frank; W E Pierce
Journal:  J Infect Dis       Date:  1966-10       Impact factor: 5.226

2.  Plasmid-mediated sulfonamide resistance in Neisseria meningitidis.

Authors:  B Facinelli; P E Varaldo
Journal:  Antimicrob Agents Chemother       Date:  1987-10       Impact factor: 5.191

3.  Mortality in meningococcal infections.

Authors:  B M Andersen
Journal:  Scand J Infect Dis       Date:  1978

4.  [Examination of the environment in meningococcal disease. Identification and clearing of the virulent microorganism from the environment of patients with meningococcal disease].

Authors:  B E Kristiansen; Y Tveten; E Ask; A B Knapskog; T Reiten; J Steen-Johnsen; G Hopen
Journal:  Tidsskr Nor Laegeforen       Date:  1989-05-10

5.  Site-specific recombination promotes linkage between trimethoprim- and sulfonamide resistance genes. Sequence characterization of dhfrV and sulI and a recombination active locus of Tn21.

Authors:  L Sundström; P Rådström; G Swedberg; O Sköld
Journal:  Mol Gen Genet       Date:  1988-08

6.  Some agent characteristics and their coexistence related to occurrence and severity of systemic meningococcal disease in Norway, Winter 1981-1982.

Authors:  K Bøvre; L O Frøholm; P Gaustad; E Holten; E A Høiby
Journal:  NIPH Ann       Date:  1983-06

7.  R-factor-mediated resistance to sulfonamides by a plasmid-borne, drug-resistant dihydropteroate synthase.

Authors:  O Sköld
Journal:  Antimicrob Agents Chemother       Date:  1976-01       Impact factor: 5.191

8.  Case fatality of meningococcal disease in western Norway.

Authors:  A Halstensen; S H Pedersen; B Haneberg; B Bjorvatn; C O Solberg
Journal:  Scand J Infect Dis       Date:  1987

9.  Meningococcal phenotypic and genotypic characteristics and human antibody levels.

Authors:  B E Kristiansen; K W Lind; K Mevold; B Sørensen; L O Frøholm; K Bryn; T Tjade; K Bøvre
Journal:  J Clin Microbiol       Date:  1988-10       Impact factor: 5.948

10.  Epidemiological patterns of meningococcal disease in Norway 1975-1979.

Authors:  K Bøvre; T W Gedde-Dahl
Journal:  NIPH Ann       Date:  1980-12
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  14 in total

1.  Physical map of the chromosome of Neisseria gonorrhoeae FA1090 with locations of genetic markers, including opa and pil genes.

Authors:  J A Dempsey; W Litaker; A Madhure; T L Snodgrass; J G Cannon
Journal:  J Bacteriol       Date:  1991-09       Impact factor: 3.490

2.  The physical map of the chromosome of a serogroup A strain of Neisseria meningitidis shows complex rearrangements relative to the chromosomes of the two mapped strains of the closely related species N. gonorrhoeae.

Authors:  J A Dempsey; A B Wallace; J G Cannon
Journal:  J Bacteriol       Date:  1995-11       Impact factor: 3.490

3.  Sulfonamide resistance in Streptococcus pyogenes is associated with differences in the amino acid sequence of its chromosomal dihydropteroate synthase.

Authors:  G Swedberg; S Ringertz; O Sköld
Journal:  Antimicrob Agents Chemother       Date:  1998-05       Impact factor: 5.191

Review 4.  Molecular techniques for the investigation of meningococcal disease epidemiology.

Authors:  M C Maiden; M Frosch
Journal:  Mol Biotechnol       Date:  2001-06       Impact factor: 2.695

Review 5.  Trimethoprim and sulfonamide resistance.

Authors:  P Huovinen; L Sundström; G Swedberg; O Sköld
Journal:  Antimicrob Agents Chemother       Date:  1995-02       Impact factor: 5.191

6.  Locations of genetic markers on the physical map of the chromosome of Neisseria gonorrhoeae FA1090.

Authors:  J A Dempsey; J G Cannon
Journal:  J Bacteriol       Date:  1994-04       Impact factor: 3.490

7.  Sulfonamide resistance in Neisseria meningitidis as defined by site-directed mutagenesis could have its origin in other species.

Authors:  C Fermer; B E Kristiansen; O Sköld; G Swedberg
Journal:  J Bacteriol       Date:  1995-08       Impact factor: 3.490

8.  PCR amplicon restriction endonuclease analysis of the chromosomal dhps gene of Neisseria meningitidis: a method for studying spread of the disease-causing strain in contacts of patients with meningococcal disease.

Authors:  B E Kristiansen; C Fermér; A Jenkins; E Ask; G Swedberg; O Sköld
Journal:  J Clin Microbiol       Date:  1995-05       Impact factor: 5.948

9.  Transformational exchanges in the dihydropteroate synthase gene of Neisseria meningitidis: a novel mechanism for acquisition of sulfonamide resistance.

Authors:  P Rådström; C Fermér; B E Kristiansen; A Jenkins; O Sköld; G Swedberg
Journal:  J Bacteriol       Date:  1992-10       Impact factor: 3.490

10.  Genealogical typing of Neisseria meningitidis.

Authors:  Xavier Didelot; Rachel Urwin; Martin C J Maiden; Daniel Falush
Journal:  Microbiology (Reading)       Date:  2009-07-30       Impact factor: 2.777
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