| Literature DB >> 21273072 |
Hao Peng1, Yongju Liang, Le Chen, Liwu Fu, Haiqin Wang, Hongwu He.
Abstract
The synthesis and biological activity of 1,3-benzenedicarbonyl dithioureas are described. Bioassay results indicated that these compounds exhibited cytotoxicity against various cancer cells. For example, compounds 4a showed the best inhibition activities against KB and CNE2 with IC(50) 10.72 and 9.91 μM, respectively.Entities:
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Year: 2011 PMID： 21273072 DOI： 10.1016/j.bmcl.2010.12.130
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823