Literature DB >> 21272727

Is fatigue after stroke associated with physical deconditioning? A cross-sectional study in ambulatory stroke survivors.

Susan J Lewis1, Amanda J Barugh, Carolyn A Greig, David H Saunders, Claire Fitzsimons, Susie Dinan-Young, Archie Young, Gillian E Mead.   

Abstract

OBJECTIVE: To determine the relationship between a measure of fatigue and 2 indices of physical fitness, lower limb extensor power (LLEP) and walking economy.
DESIGN: This was a cross-sectional study of patients with stroke. Fatigue was assessed by vitality (VIT) score of the Medical Outcomes Study 36-Item Short-Form Health Survey version 2 (SF-36v2). LLEP of the unaffected limb was measured using a lower leg extensor power rig. Walking economy was calculated by measuring oxygen consumption (mL·kg(-1)·m(-1)) during walking at a comfortable speed. Bivariate analyses were performed relating VIT to indices of fitness. Multiple regression analyses were also performed and included age, sex, and either SF-36v2 emotional role function or SF-36v2 mental health, as predictors of VIT.
SETTING: Community setting. PARTICIPANTS: Participants (N=66; 36 men; mean age ± SD, 71.0±9.9y) were all community dwelling, had survived a stroke, were able to walk independently, and had completed their stroke rehabilitation.
INTERVENTIONS: Not applicable MAIN OUTCOME MEASURES: The main outcome measure is SF-36v2 (VIT), with walking economy and LLEP of the limb unaffected by the stroke being independent variables.
RESULTS: Walking economy was not significantly related to VIT (R=-.024, P=.86, n=60). LLEP was positively related to VIT in bivariate analysis (R=.38, P=.003, n=58). After controlling for age, sex, and SF-36 emotional role function (or SF-36v2 mental health if the extreme outlier was excluded), LLEP remained a significant predictor of VIT.
CONCLUSIONS: We found an association between fatigue and reduced LLEP. If a larger study confirms these findings, it would support the need to develop and test interventions to increase LLEP as a treatment for fatigue after stroke.
Copyright © 2011 American Congress of Rehabilitation Medicine. Published by Elsevier Inc. All rights reserved.

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Mesh:

Year:  2011        PMID: 21272727     DOI: 10.1016/j.apmr.2010.10.030

Source DB:  PubMed          Journal:  Arch Phys Med Rehabil        ISSN: 0003-9993            Impact factor:   3.966


  10 in total

1.  Increased Energy Cost of Mobility in Chronic Stroke.

Authors:  Monica C Serra; Margarita S Treuth; Charlene E Hafer-Macko; Alice S Ryan
Journal:  J Gerontol Geriatr Res       Date:  2016-10-22

Review 2.  Interventions for post-stroke fatigue.

Authors:  Simiao Wu; Mansur A Kutlubaev; Ho-Yan Y Chun; Eileen Cowey; Alex Pollock; Malcolm R Macleod; Martin Dennis; Elizabeth Keane; Michael Sharpe; Gillian E Mead
Journal:  Cochrane Database Syst Rev       Date:  2015-07-02

Review 3.  Psychological associations of poststroke fatigue: a systematic review and meta-analysis.

Authors:  Simiao Wu; Amanda Barugh; Malcolm Macleod; Gillian Mead
Journal:  Stroke       Date:  2014-04-29       Impact factor: 7.914

4.  Variations in kinematics during clinical gait analysis in stroke patients.

Authors:  Julien Boudarham; Nicolas Roche; Didier Pradon; Céline Bonnyaud; Djamel Bensmail; Raphael Zory
Journal:  PLoS One       Date:  2013-06-17       Impact factor: 3.240

5.  Impaired economy of gait and decreased six-minute walk distance in Parkinson's disease.

Authors:  Leslie I Katzel; Frederick M Ivey; John D Sorkin; Richard F Macko; Barbara Smith; Lisa M Shulman
Journal:  Parkinsons Dis       Date:  2011-09-12

6.  Poststroke fatigue: who is at risk for an increase in fatigue?

Authors:  Hanna Maria van Eijsden; Ingrid Gerrie Lambert van de Port; Johanna Maria August Visser-Meily; Gert Kwakkel
Journal:  Stroke Res Treat       Date:  2011-10-19

7.  Effects of walking endurance reduction on gait stability in patients with stroke.

Authors:  M Iosa; G Morone; A Fusco; L Pratesi; M Bragoni; P Coiro; M Multari; V Venturiero; D De Angelis; S Paolucci
Journal:  Stroke Res Treat       Date:  2011-09-28

8.  Fatigue after Stroke: The Patient's Perspective.

Authors:  Victoria Louise Barbour; Gillian Elizabeth Mead
Journal:  Stroke Res Treat       Date:  2011-07-14

9.  Targeting fatigue in stroke patients.

Authors:  Andrew W Barritt; David G Smithard
Journal:  ISRN Neurol       Date:  2011-11-30

Review 10.  Factors Associated with Poststroke Fatigue: A Systematic Review.

Authors:  Amélie Ponchel; Stéphanie Bombois; Régis Bordet; Hilde Hénon
Journal:  Stroke Res Treat       Date:  2015-05-25
  10 in total

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