Literature DB >> 21272436

The fetal safety of benzodiazepines: an updated meta-analysis.

Ehijie Enato1, Myla Moretti2, Gideon Koren2.   

Abstract

Benzodiazepines are commonly used by women of reproductive age, and hence many pregnant women are exposed to them. An updated meta-analysis of their fetal safety synthesized nine studies with over one million pregnancies, yielding an odds ratio of 1.07 (95% CI 0.91 to 1.25). While benzodiazepines do not appear to increase teratogenic risk in general, case-controls suggest a twofold increased risk of oral cleft.

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Year:  2011        PMID： 21272436     DOI： 10.1016/S1701-2163(16)34772-7

Source DB:  PubMed          Journal:  J Obstet Gynaecol Can        ISSN： 1701-2163


  16 in total

Review 1.  Restless legs syndrome and pregnancy: prevalence, possible pathophysiological mechanisms and treatment.

Authors:  R Gupta; M Dhyani; T Kendzerska; S R Pandi-Perumal; A S BaHammam; P Srivanitchapoom; S Pandey; M Hallett
Journal:  Acta Neurol Scand       Date:  2015-10-19       Impact factor: 3.209

2.  Drug therapy during pregnancy: implications for dental practice.

Authors:  A Ouanounou; D A Haas
Journal:  Br Dent J       Date:  2016-04-22       Impact factor: 1.626

Review 3.  Alcohol use disorders in pregnancy.

Authors:  Jeffrey DeVido; Olivera Bogunovic; Roger D Weiss
Journal:  Harv Rev Psychiatry       Date:  2015 Mar-Apr       Impact factor: 3.732

Review 4.  IBD in pregnancy: recent advances, practical management.

Authors:  Christian P Selinger; Catherine Nelson-Piercy; Aileen Fraser; Veronica Hall; Jimmy Limdi; Lyn Smith; Marie Smith; Reem Nasur; Melanie Gunn; Andrew King; Aarthi Mohan; Khasia Mulgabal; Alexandra Kent; Klaartje Bel Kok; Tracey Glanville
Journal:  Frontline Gastroenterol       Date:  2020-05-19

Review 5.  [Psychopharmacotherapy during pregnancy : Which antipsychotics, tranquilizers and hypnotics are suitable?].

Authors:  N Bergemann; W E Paulus
Journal:  Nervenarzt       Date:  2016-09       Impact factor: 1.214

Review 6.  Canadian clinical practice guidelines for the management of anxiety, posttraumatic stress and obsessive-compulsive disorders.

Authors:  Martin A Katzman; Pierre Bleau; Pierre Blier; Pratap Chokka; Kevin Kjernisted; Michael Van Ameringen; Martin M Antony; Stéphane Bouchard; Alain Brunet; Martine Flament; Sophie Grigoriadis; Sandra Mendlowitz; Kieron O'Connor; Kiran Rabheru; Peggy M A Richter; Melisa Robichaud; John R Walker
Journal:  BMC Psychiatry       Date:  2014-07-02       Impact factor: 3.630

7.  Pregnancy and Delivery Outcomes Following Benzodiazepine Exposure: A Systematic Review and Meta-analysis.

Authors:  Sophie Grigoriadis; Lisa Graves; Miki Peer; Lana Mamisashvili; Myuri Ruthirakuhan; Parco Chan; Mirna Hennawy; Supriya Parikh; Simone Natalie Vigod; Cindy-Lee Dennis; Meir Steiner; Cara Brown; Amy Cheung; Hiltrud Dawson; Neil Rector; Melanie Guenette; Margaret Richter
Journal:  Can J Psychiatry       Date:  2020-03-09       Impact factor: 4.356

8.  A Modified Murine Embryonic Stem Cell Test for Evaluating the Teratogenic Effects of Drugs on Early Embryogenesis.

Authors:  Ruoxing Yu; Norio Miyamura; Yoshimi Okamoto-Uchida; Norie Arima; Mari Ishigami-Yuasa; Hiroyuki Kagechika; Hiroshi Nishina
Journal:  PLoS One       Date:  2015-12-18       Impact factor: 3.240

9.  First trimester exposure to anxiolytic and hypnotic drugs and the risks of major congenital anomalies: a United Kingdom population-based cohort study.

Authors:  Lu Ban; Joe West; Jack E Gibson; Linda Fiaschi; Rachel Sokal; Pat Doyle; Richard Hubbard; Liam Smeeth; Laila J Tata
Journal:  PLoS One       Date:  2014-06-25       Impact factor: 3.240

10.  Cardiac dysfunction and prenatal exposure to venlafaxine.

Authors:  Ana R Araújo; Mónica Marçal; Madalena Tuna; Rui Anjos
Journal:  Clin Case Rep       Date:  2016-03-03
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