[Modification of selected lipoproteins and blood pressure by different dosages of n-3-fatty acids].

125 male patients with cardiovascular diseases (51.0 +/- 5.1 years) were treated with supplementary fish oil diet (gelatin capsules 2 g or 6 g PUFA/a day) and arachis oil gelatin capsules, respectively, as well as simultaneous fat- and energy-reduced diet at a moderate body-training during a four-week cure. N-3 PUFA-rich fish oil diet caused a significant decrease of the triglycerides and the Apo B with increase of the HDL2 cholesterol. By addition of reduction diet the effect became clearer by additional ascertained decrease of total and LDL-cholesterol. The blood pressure-reducing effect of n-3 PUFA, but not n-6 PUFA, at test as well as on exertion was present with 2 g and 6 g/a day, however, it was more conspicuous with the higher dosage.