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Literature DB >> 21270831

Association between type 1 diabetes and GWAS SNPs in the southeast US Caucasian population.

M V Prasad Linga Reddy¹, H Wang, S Liu, B Bode, J C Reed, R D Steed, S W Anderson, L Steed, D Hopkins, J-X She.

Abstract

The present study was conducted to assess genetic associations for type 1 diabetes (T1D) reported in previous genome-wide association studies (GWAS). A total of 21 previously reported single-nucleotide polymorphisms (SNPs) were genotyped by TaqMan assays in 1434 Caucasian T1D patients and 1864 normal controls from Georgia. Analysis of the samples identified 18 SNPs (PTPN22, INS, IFIH1, SH2B3, ERBB3, CTLA4, C14orf181, CTSH, CLEC16A, CD69, ITPR3, C6orf173, SKAP2, PRKCQ, RNLS, IL27, SIRPG and CTRB2) with putative association.

Entities: Chemical Disease Gene Mutation Species

Mesh：

Year: 2011 PMID： 21270831 PMCID： PMC3952552 DOI： 10.1038/gene.2010.70

Source DB: PubMed Journal: Genes Immun ISSN： 1466-4879 Impact factor: 2.676

25 in total

1. Rapid genotyping of single nucleotide polymorphisms using novel minor groove binding DNA oligonucleotides (MGB probes).

Authors: Jacques B de Kok; Erwin T G Wiegerinck; Belinda A J Giesendorf; Dorine W Swinkels
Journal: Hum Mutat Date: 2002-05 Impact factor: 4.878

2. A genome-wide association study identifies novel risk loci for type 2 diabetes.

Authors: Robert Sladek; Ghislain Rocheleau; Johan Rung; Christian Dina; Lishuang Shen; David Serre; Philippe Boutin; Daniel Vincent; Alexandre Belisle; Samy Hadjadj; Beverley Balkau; Barbara Heude; Guillaume Charpentier; Thomas J Hudson; Alexandre Montpetit; Alexey V Pshezhetsky; Marc Prentki; Barry I Posner; David J Balding; David Meyre; Constantin Polychronakos; Philippe Froguel
Journal: Nature Date: 2007-02-11 Impact factor: 49.962

3. Statistical false positive or true disease pathway?

Authors: John A Todd
Journal: Nat Genet Date: 2006-07 Impact factor: 38.330

4. A genome-wide association study of nonsynonymous SNPs identifies a type 1 diabetes locus in the interferon-induced helicase (IFIH1) region.

Authors: Deborah J Smyth; Jason D Cooper; Rebecca Bailey; Sarah Field; Oliver Burren; Luc J Smink; Cristian Guja; Constantin Ionescu-Tirgoviste; Barry Widmer; David B Dunger; David A Savage; Neil M Walker; David G Clayton; John A Todd
Journal: Nat Genet Date: 2006-05-14 Impact factor: 38.330

5. Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels.

Authors: Richa Saxena; Benjamin F Voight; Valeriya Lyssenko; Noël P Burtt; Paul I W de Bakker; Hong Chen; Jeffrey J Roix; Sekar Kathiresan; Joel N Hirschhorn; Mark J Daly; Thomas E Hughes; Leif Groop; David Altshuler; Peter Almgren; Jose C Florez; Joanne Meyer; Kristin Ardlie; Kristina Bengtsson Boström; Bo Isomaa; Guillaume Lettre; Ulf Lindblad; Helen N Lyon; Olle Melander; Christopher Newton-Cheh; Peter Nilsson; Marju Orho-Melander; Lennart Råstam; Elizabeth K Speliotes; Marja-Riitta Taskinen; Tiinamaija Tuomi; Candace Guiducci; Anna Berglund; Joyce Carlson; Lauren Gianniny; Rachel Hackett; Liselotte Hall; Johan Holmkvist; Esa Laurila; Marketa Sjögren; Maria Sterner; Aarti Surti; Margareta Svensson; Malin Svensson; Ryan Tewhey; Brendan Blumenstiel; Melissa Parkin; Matthew Defelice; Rachel Barry; Wendy Brodeur; Jody Camarata; Nancy Chia; Mary Fava; John Gibbons; Bob Handsaker; Claire Healy; Kieu Nguyen; Casey Gates; Carrie Sougnez; Diane Gage; Marcia Nizzari; Stacey B Gabriel; Gung-Wei Chirn; Qicheng Ma; Hemang Parikh; Delwood Richardson; Darrell Ricke; Shaun Purcell
Journal: Science Date: 2007-04-26 Impact factor: 47.728

6. A novel susceptibility locus for type 1 diabetes on Chr12q13 identified by a genome-wide association study.

Authors: Hakon Hakonarson; Hui-Qi Qu; Jonathan P Bradfield; Luc Marchand; Cecilia E Kim; Joseph T Glessner; Rosemarie Grabs; Tracy Casalunovo; Shayne P Taback; Edward C Frackelton; Andrew W Eckert; Kiran Annaiah; Margaret L Lawson; F George Otieno; Erin Santa; Julie L Shaner; Ryan M Smith; Chioma C Onyiah; Robert Skraban; Rosetta M Chiavacci; Luke J Robinson; Charles A Stanley; Susan E Kirsch; Marcella Devoto; Dimitri S Monos; Struan F A Grant; Constantin Polychronakos
Journal: Diabetes Date: 2008-01-15 Impact factor: 9.461

7. Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes.

Authors: Jeffrey C Barrett; David G Clayton; Patrick Concannon; Beena Akolkar; Jason D Cooper; Henry A Erlich; Cécile Julier; Grant Morahan; Jørn Nerup; Concepcion Nierras; Vincent Plagnol; Flemming Pociot; Helen Schuilenburg; Deborah J Smyth; Helen Stevens; John A Todd; Neil M Walker; Stephen S Rich
Journal: Nat Genet Date: 2009-05-10 Impact factor: 38.330

8. Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes.

Authors: John A Todd; Neil M Walker; Jason D Cooper; Deborah J Smyth; Kate Downes; Vincent Plagnol; Rebecca Bailey; Sergey Nejentsev; Sarah F Field; Felicity Payne; Christopher E Lowe; Jeffrey S Szeszko; Jason P Hafler; Lauren Zeitels; Jennie H M Yang; Adrian Vella; Sarah Nutland; Helen E Stevens; Helen Schuilenburg; Gillian Coleman; Meeta Maisuria; William Meadows; Luc J Smink; Barry Healy; Oliver S Burren; Alex A C Lam; Nigel R Ovington; James Allen; Ellen Adlem; Hin-Tak Leung; Chris Wallace; Joanna M M Howson; Cristian Guja; Constantin Ionescu-Tîrgovişte; Matthew J Simmonds; Joanne M Heward; Stephen C L Gough; David B Dunger; Linda S Wicker; David G Clayton
Journal: Nat Genet Date: 2007-06-06 Impact factor: 38.330

9. Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls.

Authors:
Journal: Nature Date: 2007-06-07 Impact factor: 49.962

10. Systematic association mapping identifies NELL1 as a novel IBD disease gene.

Authors: Andre Franke; Jochen Hampe; Philip Rosenstiel; Christian Becker; Florian Wagner; Robert Häsler; Randall D Little; Klaus Huse; Andreas Ruether; Tobias Balschun; Michael Wittig; Abdou Elsharawy; Gabriele Mayr; Mario Albrecht; Natalie J Prescott; Clive M Onnie; Hélène Fournier; Tim Keith; Uwe Radelof; Matthias Platzer; Christopher G Mathew; Monika Stoll; Michael Krawczak; Peter Nürnberg; Stefan Schreiber
Journal: PLoS One Date: 2007-08-08 Impact factor: 3.240

47 in total

1. rs11203203 is associated with type 1 diabetes risk in population pre-screened for high-risk HLA-DR,DQ genotypes.

Authors: Kelly Johnson; Randall Wong; Katherine J Barriga; Georgeanna Klingensmith; Anette-G Ziegler; Marian J Rewers; Andrea K Steck
Journal: Pediatr Diabetes Date: 2012-07-08 Impact factor: 4.866

2. Hypomethylation within gene promoter regions and type 1 diabetes in discordant monozygotic twins.

Authors: Emon Elboudwarej; Michael Cole; Farren B S Briggs; Alexandra Fouts; Pamela R Fain; Hong Quach; Diana Quach; Elizabeth Sinclair; Lindsey A Criswell; Julie A Lane; Andrea K Steck; Lisa F Barcellos; Janelle A Noble
Journal: J Autoimmun Date: 2016-01-09 Impact factor: 7.094

3. Autoimmunity-associated intronic SNP (rs2281808) detected by a simple phenotypic assay: Unique case or broader opportunity?

Authors: Sushmita Sinha; Pranav S Renavikar; Michael P Crawford; Jake W Rodgers; Eva Tsalikian; Michael Tansey; Nitin J Karandikar
Journal: Clin Immunol Date: 2018-12-21 Impact factor: 3.969

Review 4. Molecular mechanisms in autoimmune type 1 diabetes: a critical review.

Authors: Zhiguo Xie; Christopher Chang; Zhiguang Zhou
Journal: Clin Rev Allergy Immunol Date: 2014-10 Impact factor: 8.667

Review 5. The yin and yang of protein kinase C-theta (PKCθ): a novel drug target for selective immunosuppression.

Authors: Elizabeth Yan Zhang; Kok-Fai Kong; Amnon Altman
Journal: Adv Pharmacol Date: 2013

6. Genome-wide association study identified the human leukocyte antigen region as a novel locus for plasma beta-2 microglobulin.

Authors: Adrienne Tin; Brad C Astor; Eric Boerwinkle; Ron C Hoogeveen; Josef Coresh; Wen Hong Linda Kao
Journal: Hum Genet Date: 2013-02-16 Impact factor: 4.132

Review 7. Selective IgA deficiency in autoimmune diseases.

Authors: Ning Wang; Nan Shen; Timothy J Vyse; Vidya Anand; Iva Gunnarson; Gunnar Sturfelt; Solbritt Rantapää-Dahlqvist; Kerstin Elvin; Lennart Truedsson; Bengt A Andersson; Charlotte Dahle; Eva Ortqvist; Peter K Gregersen; Timothy W Behrens; Lennart Hammarström
Journal: Mol Med Date: 2011-08-04 Impact factor: 6.354