UNLABELLED: The aim of this study was to determine the uptake of L-[methyl-(11)C]-methionine ((11)C-MET) in the normal brain of patients younger than 20 y, to facilitate more accurate diagnoses in young patients. METHODS: Eighty-two patients were categorized into 4 groups according to their age. They underwent (11)C-MET PET, and a standardized uptake value (SUV) was determined for different brain regions including the frontal lobe, parietal lobe, cerebellum, and brain stem. RESULTS: Compared with all other parts of the brain, the cerebellum had the highest SUV. A tendency for a positive relationship between SUV and age was found in all regions, and a significant relationship with SUV was found in the frontal lobe and cerebellum. CONCLUSION: The character of SUV in the normal brains of children is different from that of adults, and these normal SUV data will play an important role as a critical reference value.
UNLABELLED: The aim of this study was to determine the uptake of L-[methyl-(11)C]-methionine ((11)C-MET) in the normal brain of patients younger than 20 y, to facilitate more accurate diagnoses in young patients. METHODS: Eighty-two patients were categorized into 4 groups according to their age. They underwent (11)C-MET PET, and a standardized uptake value (SUV) was determined for different brain regions including the frontal lobe, parietal lobe, cerebellum, and brain stem. RESULTS: Compared with all other parts of the brain, the cerebellum had the highest SUV. A tendency for a positive relationship between SUV and age was found in all regions, and a significant relationship with SUV was found in the frontal lobe and cerebellum. CONCLUSION: The character of SUV in the normal brains of children is different from that of adults, and these normal SUV data will play an important role as a critical reference value.
Authors: Sebastian M Harris; James C Davis; Scott E Snyder; Elizabeth R Butch; Amy L Vavere; Mehmet Kocak; Barry L Shulkin Journal: J Nucl Med Date: 2013-09-19 Impact factor: 10.057
Authors: Andor W J M Glaudemans; Roelien H Enting; Mart A A M Heesters; Rudi A J O Dierckx; Ronald W J van Rheenen; Annemiek M E Walenkamp; Riemer H J A Slart Journal: Eur J Nucl Med Mol Imaging Date: 2012-12-12 Impact factor: 9.236