Literature DB >> 21269596

Ritonavir-induced acute kidney injury: kidney biopsy findings and review of literature.

T Shafi1, M J Choi, L C Racusen, L A Spacek, C Berry, M Atta, D M Fine.   

Abstract

Ritonavir therapy is not generally considered nephrotoxic. We report a case of acute kidney injury secondary to ritonavir, with kidney biopsy demonstrating extensive acute tubular injury. This is the first report of a kidney biopsy and pathology in acute kidney injury associated with ritonavir. A review of published medical literature on the topic is also presented.

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Year:  2011        PMID: 21269596      PMCID: PMC3727453          DOI: 10.5414/cn106469

Source DB:  PubMed          Journal:  Clin Nephrol        ISSN: 0301-0430            Impact factor:   0.975


  12 in total

1.  Two episodes of acute renal failure, rhabdomyolysis, and severe hepatitis in an AIDS patient successively treated with ritonavir and indinavir.

Authors:  O Benveniste; P Longuet; X Duval; V Le Moing; C Leport; J L Vildé
Journal:  Clin Infect Dis       Date:  1999-05       Impact factor: 9.079

2.  Renal insufficiency induced by ritonavir in HIV-infected patients.

Authors:  M V Bochet; C Jacquiaud; M A Valantin; C Katlama; G Deray
Journal:  Am J Med       Date:  1998-11       Impact factor: 4.965

3.  Pancreatorenal syndrome associated with combination antiretroviral therapy in HIV infection.

Authors:  R B Stricker; K M Man; D B Bouvier; D A Goldberg; A E Mendiola
Journal:  Lancet       Date:  1997-06-14       Impact factor: 79.321

4.  Renal failure after treatment with ritonavir.

Authors:  M Duong; C Sgro; M Grappin; F Biron; A Boibieux
Journal:  Lancet       Date:  1996-09-07       Impact factor: 79.321

Review 5.  Tenofovir-associated acute and chronic kidney disease: a case of multiple drug interactions.

Authors:  Anthony E Zimmermann; Thomas Pizzoferrato; John Bedford; Anne Morris; Robert Hoffman; Gregory Braden
Journal:  Clin Infect Dis       Date:  2005-12-08       Impact factor: 9.079

6.  Interactions of HIV protease inhibitors with ATP-dependent drug export proteins.

Authors:  H Gutmann; G Fricker; J Drewe; M Toeroek; D S Miller
Journal:  Mol Pharmacol       Date:  1999-08       Impact factor: 4.436

7.  Antiretroviral treatment of adult HIV infection: 2008 recommendations of the International AIDS Society-USA panel.

Authors:  Scott M Hammer; Joseph J Eron; Peter Reiss; Robert T Schooley; Melanie A Thompson; Sharon Walmsley; Pedro Cahn; Margaret A Fischl; Jose M Gatell; Martin S Hirsch; Donna M Jacobsen; Julio S G Montaner; Douglas D Richman; Patrick G Yeni; Paul A Volberding
Journal:  JAMA       Date:  2008-08-06       Impact factor: 56.272

8.  Anti-nuclear, anti-neutrophil cytoplasmic and anti-glomerular basement membrane antibodies in HIV-infected individuals.

Authors:  J A Savige; L Chang; S Horn; S M Crowe
Journal:  Autoimmunity       Date:  1994       Impact factor: 2.815

9.  Glomerular lesions in HIV-positive patients: a 20-year biopsy experience from Northern Italy.

Authors:  M Nebuloni; G Barbiano di Belgiojoso; A Genderini; A Tosoni; N L; M Heidempergher; P Zerbi; L Vago
Journal:  Clin Nephrol       Date:  2009-07       Impact factor: 0.975

10.  Acute renal failure associated with immunoglobulin therapy.

Authors:  T G Cantú; E W Hoehn-Saric; K M Burgess; L Racusen; P J Scheel
Journal:  Am J Kidney Dis       Date:  1995-02       Impact factor: 8.860

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  9 in total

1.  The Opportunities of Metabolomics in Drug Safety Evaluation.

Authors:  Pengcheng Wang; Amina I Shehu; Xiaochao Ma
Journal:  Curr Pharmacol Rep       Date:  2017-01-03

2.  Metabolomic screening and identification of the bioactivation pathways of ritonavir.

Authors:  Feng Li; Jie Lu; Xiaochao Ma
Journal:  Chem Res Toxicol       Date:  2011-11-17       Impact factor: 3.739

3.  Renal stone composed of ritonavir.

Authors:  Anna M Zhao; Nancy R Angoff
Journal:  BMJ Case Rep       Date:  2019-07-01

4.  Kidney disease in the setting of HIV infection: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference.

Authors:  Charles R Swanepoel; Mohamed G Atta; Vivette D D'Agati; Michelle M Estrella; Agnes B Fogo; Saraladevi Naicker; Frank A Post; Nicola Wearne; Cheryl A Winkler; Michael Cheung; David C Wheeler; Wolfgang C Winkelmayer; Christina M Wyatt
Journal:  Kidney Int       Date:  2018-02-03       Impact factor: 10.612

5.  Severe Inflammation, Acute Kidney Injury, and Drug-Drug Interaction: Triple Penalty for Prolonged Elimination of Apixaban in Patients With Coronavirus Disease 2019: A Grand Round.

Authors:  Manon Launay; Anne-Laure Demartin; Sophie Perinel Ragey; Patrick Mismetti; Elisabeth Botelho-Nevers; Xavier Delavenne
Journal:  Ther Drug Monit       Date:  2021-08-01       Impact factor: 3.681

6.  HIV protease inhibitor ritonavir induces renal fibrosis and dysfunction: role of platelet-derived TGF-β1 and intervention via antioxidant pathways.

Authors:  Jeffrey Laurence; Sonia Elhadad; Sandra Gostynska; Zhongxin Yu; Hunter Terry; Rohan Varshney; Kar-Ming Fung; Mary E Choi; Jasimuddin Ahamed
Journal:  AIDS       Date:  2020-06-01       Impact factor: 4.632

7.  Improved kidney function in patients who switch their protease inhibitor from atazanavir or lopinavir to darunavir.

Authors:  Sophie Jose; Mark Nelson; Andrew Phillips; David Chadwick; Roy Trevelion; Rachael Jones; Deborah I Williams; Lisa Hamzah; Caroline A Sabin; Frank A Post
Journal:  AIDS       Date:  2017-02-20       Impact factor: 4.177

8.  Approach to acute kidney injury in HIV-infected patients in South Africa.

Authors:  Michael T Boswell; Theresa M Rossouw
Journal:  South Afr J HIV Med       Date:  2017-11-28       Impact factor: 2.744

Review 9.  The Potential of Spirulina platensis to Ameliorate the Adverse Effects of Highly Active Antiretroviral Therapy (HAART).

Authors:  Thabani Sibiya; Terisha Ghazi; Anil Chuturgoon
Journal:  Nutrients       Date:  2022-07-27       Impact factor: 6.706

  9 in total

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