Literature DB >> 21268583

A domino approach (hydrolysis/dehydrohalogenation/Heck coupling) for the synthesis of styrene sulfonate salts.

G K Surya Prakash1, Parag V Jog, Hema S Krishnan, George A Olah.   

Abstract

A domino approach of hydrolysis/dehydrohalogenation/Heck coupling was used to synthesize styrene sulfonate salts from iodoarenes and chloroethanesulfonyl chloride in good to excellent yields. Methodology was applicable for heterocyclic as well as disubstituted iodoarenes. Some of the key features of this synthetic methodology include the use of phosphine free catalytic system, water as an environmentally friendly solvent, short reaction times, and absence of additives.

Entities:  

Year:  2011        PMID: 21268583     DOI: 10.1021/ja111462h

Source DB:  PubMed          Journal:  J Am Chem Soc        ISSN: 0002-7863            Impact factor:   15.419


  2 in total

1.  In situ synthesis of alkenyl tetrazines for highly fluorogenic bioorthogonal live-cell imaging probes.

Authors:  Haoxing Wu; Jun Yang; Jolita Šečkutė; Neal K Devaraj
Journal:  Angew Chem Int Ed Engl       Date:  2014-04-24       Impact factor: 15.336

2.  A Heck-Matsuda Process for the Synthesis of β-Arylethenesulfonyl Fluorides: Selectively Addressable Bis-electrophiles for SuFEx Click Chemistry.

Authors:  Hua-Li Qin; Qinheng Zheng; Grant A L Bare; Peng Wu; K Barry Sharpless
Journal:  Angew Chem Int Ed Engl       Date:  2016-10-10       Impact factor: 15.336

  2 in total

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