Literature DB >> 21264375

nanoLAB: an ultraportable, handheld diagnostic laboratory for global health.

Richard S Gaster1, Drew A Hall, Shan X Wang.   

Abstract

Driven by scientific progress and economic stimulus, medical diagnostics will move to a stage in which straightforward medical diagnoses are independent of physician visits and large centralized laboratories. The future of basic diagnostic medicine will lie in the hands of private individuals. We have taken significant strides towards achieving this goal by developing an autoassembly assay for disease biomarker detection which obviates the need for washing steps and is run on a handheld sensing platform. By coupling magnetic nanotechnology with an array of magnetically responsive nanosensors, we demonstrate a rapid, multiplex immunoassay that eliminates the need for trained technicians to run molecular diagnostic tests. Furthermore, the platform is battery-powered and ultraportable, allowing the assay to be run anywhere in the world by any individual.

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Year:  2011        PMID: 21264375     DOI: 10.1039/c0lc00534g

Source DB:  PubMed          Journal:  Lab Chip        ISSN: 1473-0189            Impact factor:   6.799


  29 in total

1.  Perspective on diagnostics for global health.

Authors:  Elain Fu; Paul Yager; Pierre N Floriano; Nicolaos Christodoulides; John T McDevitt
Journal:  IEEE Pulse       Date:  2011-11       Impact factor: 0.924

2.  High-Resolution Analysis of Antibodies to Post-Translational Modifications Using Peptide Nanosensor Microarrays.

Authors:  Jung-Rok Lee; D James Haddon; Nidhi Gupta; Jordan V Price; Grace M Credo; Vivian K Diep; Kyunglok Kim; Drew A Hall; Emily C Baechler; Michelle Petri; Madoo Varma; Paul J Utz; Shan X Wang
Journal:  ACS Nano       Date:  2016-09-20       Impact factor: 15.881

3.  A 256 pixel magnetoresistive biosensor microarray in 0.18μm CMOS.

Authors:  Drew A Hall; Richard S Gaster; Kofi Makinwa; Shan X Wang; Boris Murmann
Journal:  IEEE J Solid-State Circuits       Date:  2013-05       Impact factor: 5.013

4.  Biosensors: magnets tackle kinetic questions.

Authors:  Shawn P Mulvaney
Journal:  Nat Nanotechnol       Date:  2011-05       Impact factor: 39.213

Review 5.  Strategies in Ebola virus disease (EVD) diagnostics at the point of care.

Authors:  Chad T Coarsey; Nwadiuto Esiobu; Ramswamy Narayanan; Mirjana Pavlovic; Hadi Shafiee; Waseem Asghar
Journal:  Crit Rev Microbiol       Date:  2017-04-25       Impact factor: 7.624

6.  Point-of-care rare cell cancer diagnostics.

Authors:  David Issadore
Journal:  Methods Mol Biol       Date:  2015

7.  Combined reflection and transmission microscope for telemedicine applications in field settings.

Authors:  Gabriel Biener; Alon Greenbaum; Serhan O Isikman; Kelvin Lee; Derek Tseng; Aydogan Ozcan
Journal:  Lab Chip       Date:  2011-06-27       Impact factor: 6.799

Review 8.  Microchip-based detection of magnetically labeled cancer biomarkers.

Authors:  Melaku Muluneh; David Issadore
Journal:  Adv Drug Deliv Rev       Date:  2013-10-05       Impact factor: 15.470

9.  Quantification of protein interactions and solution transport using high-density GMR sensor arrays.

Authors:  Richard S Gaster; Liang Xu; Shu-Jen Han; Robert J Wilson; Drew A Hall; Sebastian J Osterfeld; Heng Yu; Shan X Wang
Journal:  Nat Nanotechnol       Date:  2011-04-10       Impact factor: 39.213

10.  Design Considerations for CMOS-Integrated Hall-Effect Magnetic Bead Detectors for Biosensor Applications.

Authors:  K Skucha; S Gambini; P Liu; M Megens; J Kim; Be Boser
Journal:  J Microelectromech Syst       Date:  2013-06-05       Impact factor: 2.417

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