Literature DB >> 21263663

Visualization of microvasculature by dual-beam phase-resolved Doppler optical coherence tomography.

Stefan Zotter1, Michael Pircher, Teresa Torzicky, Marco Bonesi, Erich Götzinger, Rainer A Leitgeb, Christoph K Hitzenberger.   

Abstract

We present a dual-beam Doppler optical coherence tomography system for visualizing the microvasculature within the retina. The sample arm beams from two identical spectral domain optical coherence tomography (SD-OCT) systems are combined such that there is a small horizontal offset between them at the retina. Thereby we record two tomograms which are slightly separated in time. Phase-resolved Doppler analysis is performed between these two data sets. This system allows blood capillary imaging with high flow sensitivity and variable velocity range. To demonstrate the performance of our system we present images of the microvascular network around the fovea and around the optic nerve head of the human eye.

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Mesh:

Year:  2011        PMID: 21263663      PMCID: PMC3036955          DOI: 10.1364/OE.19.001217

Source DB:  PubMed          Journal:  Opt Express        ISSN: 1094-4087            Impact factor:   3.894


  31 in total

1.  Spectral-domain phase microscopy.

Authors:  Michael A Choma; Audrey K Ellerbee; Changhuei Yang; Tony L Creazzo; Joseph A Izatt
Journal:  Opt Lett       Date:  2005-05-15       Impact factor: 3.776

2.  Noninvasive imaging of in vivo blood flow velocity using optical Doppler tomography.

Authors:  Z Chen; T E Milner; S Srinivas; X Wang; A Malekafzali; M J van Gemert; J S Nelson
Journal:  Opt Lett       Date:  1997-07-15       Impact factor: 3.776

3.  In vivo bidirectional color Doppler flow imaging of picoliter blood volumes using optical coherence tomography.

Authors:  J A Izatt; M D Kulkarni; S Yazdanfar; J K Barton; A J Welch
Journal:  Opt Lett       Date:  1997-09-15       Impact factor: 3.776

4.  Scanning protocols dedicated to smart velocity ranging in spectral OCT.

Authors:  Ireneusz Grulkowski; Iwona Gorczynska; Maciej Szkulmowski; Daniel Szlag; Anna Szkulmowska; Rainer A Leitgeb; Andrzej Kowalczyk; Maciej Wojtkowski
Journal:  Opt Express       Date:  2009-12-21       Impact factor: 3.894

5.  Mobility and transverse flow visualization using phase variance contrast with spectral domain optical coherence tomography.

Authors:  Jeff Fingler; Dan Schwartz; Changhuei Yang; Scott E Fraser
Journal:  Opt Express       Date:  2007-10-01       Impact factor: 3.894

6.  Three dimensional optical angiography.

Authors:  Ruikang K Wang; Steven L Jacques; Zhenhe Ma; Sawan Hurst; Stephen R Hanson; Andras Gruber
Journal:  Opt Express       Date:  2007-04-02       Impact factor: 3.894

7.  Optical coherence tomography.

Authors:  D Huang; E A Swanson; C P Lin; J S Schuman; W G Stinson; W Chang; M R Hee; T Flotte; K Gregory; C A Puliafito
Journal:  Science       Date:  1991-11-22       Impact factor: 47.728

8.  Depth-resolved imaging of capillary networks in retina and choroid using ultrahigh sensitive optical microangiography.

Authors:  Ruikang K Wang; Lin An; Peter Francis; David J Wilson
Journal:  Opt Lett       Date:  2010-05-01       Impact factor: 3.776

9.  Dual-beam Fourier domain optical Doppler tomography of zebrafish.

Authors:  Nicusor V Iftimia; Daniel X Hammer; R D Ferguson; Mircea Mujat; Danthu Vu; Anthony A Ferrante
Journal:  Opt Express       Date:  2008-09-01       Impact factor: 3.894

10.  Three-dimensional microscopy of the tumor microenvironment in vivo using optical frequency domain imaging.

Authors:  Benjamin J Vakoc; Ryan M Lanning; James A Tyrrell; Timothy P Padera; Lisa A Bartlett; Triantafyllos Stylianopoulos; Lance L Munn; Guillermo J Tearney; Dai Fukumura; Rakesh K Jain; Brett E Bouma
Journal:  Nat Med       Date:  2009-09-13       Impact factor: 53.440

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  54 in total

Review 1.  Methods and algorithms for optical coherence tomography-based angiography: a review and comparison.

Authors:  Anqi Zhang; Qinqin Zhang; Chieh-Li Chen; Ruikang K Wang
Journal:  J Biomed Opt       Date:  2015-10       Impact factor: 3.170

2.  Expansions of the neurovascular scleral canal and contained optic nerve occur early in the hypertonic saline rat experimental glaucoma model.

Authors:  Marta Pazos; Hongli Yang; Stuart K Gardiner; William O Cepurna; Elaine C Johnson; John C Morrison; Claude F Burgoyne
Journal:  Exp Eye Res       Date:  2015-10-22       Impact factor: 3.467

3.  Statistical analysis of motion contrast in optical coherence tomography angiography.

Authors:  Yuxuan Cheng; Li Guo; Cong Pan; Tongtong Lu; Tianyu Hong; Zhihua Ding; Peng Li
Journal:  J Biomed Opt       Date:  2015-11       Impact factor: 3.170

4.  OCT angiography by absolute intensity difference applied to normal and diseased human retinas.

Authors:  Daniel Ruminski; Bartosz L Sikorski; Danuta Bukowska; Maciej Szkulmowski; Krzysztof Krawiec; Grazyna Malukiewicz; Lech Bieganowski; Maciej Wojtkowski
Journal:  Biomed Opt Express       Date:  2015-07-06       Impact factor: 3.732

Review 5.  Imaging of the parafoveal capillary network in diabetes.

Authors:  Gábor György Deák; Ursula Schmidt-Erfurth
Journal:  Curr Diab Rep       Date:  2013-08       Impact factor: 4.810

6.  Space-division multiplexing optical coherence tomography.

Authors:  Chao Zhou; Aneesh Alex; Janarthanan Rasakanthan; Yutao Ma
Journal:  Opt Express       Date:  2013-08-12       Impact factor: 3.894

7.  Imaging of vascular wall fine structure in the human retina using adaptive optics scanning laser ophthalmoscopy.

Authors:  Toco Y P Chui; Thomas J Gast; Stephen A Burns
Journal:  Invest Ophthalmol Vis Sci       Date:  2013-10-29       Impact factor: 4.799

8.  Path-length-multiplexed scattering-angle-diverse optical coherence tomography for retinal imaging.

Authors:  Bingqing Wang; Biwei Yin; Jordan Dwelle; H Grady Rylander; Mia K Markey; Thomas E Milner
Journal:  Opt Lett       Date:  2013-11-01       Impact factor: 3.776

9.  Comparison of adaptive optics scanning light ophthalmoscopic fluorescein angiography and offset pinhole imaging.

Authors:  Toco Y P Chui; Michael Dubow; Alexander Pinhas; Nishit Shah; Alexander Gan; Rishard Weitz; Yusufu N Sulai; Alfredo Dubra; Richard B Rosen
Journal:  Biomed Opt Express       Date:  2014-03-13       Impact factor: 3.732

10.  Wide-field imaging of retinal vasculature using optical coherence tomography-based microangiography provided by motion tracking.

Authors:  Qinqin Zhang; Yanping Huang; Thomas Zhang; Sophie Kubach; Lin An; Michal Laron; Utkarsh Sharma; Ruikang K Wang
Journal:  J Biomed Opt       Date:  2015-06       Impact factor: 3.170

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