| Literature DB >> 21262329 |
Zhen-Liang Sun1, Gang-Long Gao, Yin-Fang Xia, Jing Feng, Zeng-Yong Qiao.
Abstract
A new triterpenoid saponin, named semenoside A (1), was isolated from Semen Celosia cristatae. Its structure was elucidated on the basis of 1D, 2D NMR, HR-FAB-MS and ESI-MS techniques, and physicochemical properties. The hepatoprotective activity of semenoside A with an oral dose of 1.0, 2.0 and 4.0mg/kg, respectively, were investigated by carbon tetrachloride (CCl(4))-induced hepatotoxicity in mice. The results indicated that it had significant hepatoprotective effects (p < 0.01).Entities:
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Year: 2011 PMID： 21262329 DOI： 10.1016/j.fitote.2011.01.007
Source DB: PubMed Journal: Fitoterapia ISSN： 0367-326X Impact factor: 2.882